DRSC/TRiP Functional Genomics Resources

powered by:
logo

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment Ppa and Fbxl5

DIOPT Version :9

Sequence 1:NP_001261138.1 Gene:Ppa / 37602 FlyBaseID:FBgn0020257 Length:562 Species:Drosophila melanogaster
Sequence 2:XP_006251138.1 Gene:Fbxl5 / 305424 RGDID:1306887 Length:690 Species:Rattus norvegicus


Alignment Length:510 Identity:109/510 - (21%)
Similarity:178/510 - (34%) Gaps:161/510 - (31%)


- Green bases have known domain annotations that are detailed below.


  Fly   147 THISNLFPELLEQIFEHLPVRDLGRAAQVCTAWRDAAYAKSVWKGVEAKLHLKR----SSPS--- 204
            |.|::|.||::..||.:|..::|.|.:||.|.|...|...|:||.: ..:|..|    |.|:   
  Rat   203 TGITHLPPEVMLSIFSYLNPQELCRCSQVSTKWSQLAKTGSLWKHL-YPVHWARGDWYSGPATEL 266

  Fly   205 -------------------------------------------------LFNCLVKRGIKKVQIL 220
                                                             |.:.|:...:..|   
  Rat   267 DTEPDEEWVRSRKDESRAFQEWDEDADIDESEESAEESVAISIAQMEKRLLHGLIHNVLPYV--- 328

  Fly   221 SLRRSLKDLVLGVPALTSLN-----LSGCFNVADMNLGHAFSVD-----------LPNLKTLDLS 269
              ..|:|.|||...:..|..     |..|.|:..::|......|           ..:|:.||||
  Rat   329 --GTSVKTLVLAYSSAVSSKMVRQILELCPNLEHLDLTQTDISDSAFDSWSWLGCCQSLRHLDLS 391

  Fly   270 LCKQITDTSLGRIAQHLRNLETLELG---GCCNITNTGLLLIAWGLK--KLKHLNLRSCWH-ISD 328
            .|::|||.:|.:|::.|..|.:.:.|   .....|:|     .|..|  .:......:|.| :::
  Rat   392 GCEKITDMALEKISRALGVLTSHQSGVLKSAGKTTST-----PWTNKDITMPSTTQYACLHNLTN 451

  Fly   329 QGIG------HLAGFSRETAEGNLQLEYLGLQDCQRLSD------------EAL---------GH 366
            :|:|      |.  ::...:..:....|:.:.|.:.|:|            |:|         |.
  Rat   452 KGVGEEIDSEHT--WTEPVSSESFTPPYVWMLDAEDLADIEDAVEWRHRNVESLCVMETASNFGC 514

  Fly   367 IAQGLTSLKSINL--------------------SFCVSVTDSGLKHLARMPKLEQLNLRSCDNIS 411
            .:.|..|...:.|                    |||  .|.:.|:.::.:|....:..::.....
  Rat   515 SSSGCYSKDIVGLRTSVCWQQHCASPAFAYCGHSFC--CTGTALRTMSALPAASAVCRKALRTTL 577

  Fly   412 DIGMAYLTEGGSGINSLDVSFCDKISDQALTHIAQGLYRLRSLSLNQC-QITDHGM--LKIAKAL 473
            ..|...            :.|..:.|||....:      |..|||:.| ||||||:  |.:...|
  Rat   578 PRGKDL------------IYFGSEKSDQETGRV------LLFLSLSGCYQITDHGLRVLTLGGGL 624

  Fly   474 HELENLNIGQCSRITDKGLQTLAEDLTNLKTIDLYGCTQLSSKGIDIIMKLPKLQ 528
            ..||:||:..|..:|..|||.|.....:|.....|.|..::....|.......||
  Rat   625 PYLEHLNLSGCLTVTGAGLQDLVSACPSLNDEYFYYCDNINGPHADTASGCQNLQ 679

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
PpaNP_001261138.1 F-box-like 149..190 CDD:289689 15/40 (38%)
AMN1 <226..>334 CDD:187754 32/135 (24%)
leucine-rich repeat 236..256 CDD:275381 5/24 (21%)
leucine-rich repeat 263..288 CDD:275381 12/24 (50%)
leucine-rich repeat 289..314 CDD:275381 6/29 (21%)
leucine-rich repeat 315..347 CDD:275381 5/38 (13%)
AMN1 347..524 CDD:187754 48/220 (22%)
leucine-rich repeat 348..373 CDD:275381 8/45 (18%)
leucine-rich repeat 374..398 CDD:275381 6/43 (14%)
leucine-rich repeat 399..424 CDD:275381 1/24 (4%)
leucine-rich repeat 425..450 CDD:275381 4/24 (17%)
leucine-rich repeat 451..475 CDD:275381 13/26 (50%)
leucine-rich repeat 476..501 CDD:275381 10/24 (42%)
Fbxl5XP_006251138.1 Hr_FBXL5 7..160 CDD:213984
F-box-like 205..249 CDD:289689 17/44 (39%)
leucine-rich repeat 332..345 CDD:275381 4/12 (33%)
AMN1 <340..>404 CDD:187754 16/63 (25%)
leucine-rich repeat 358..384 CDD:275381 2/25 (8%)
leucine-rich repeat 385..448 CDD:275381 19/67 (28%)
leucine-rich repeat 449..516 CDD:275381 10/68 (15%)
leucine-rich repeat 540..571 CDD:275381 6/32 (19%)
leucine-rich repeat 573..626 CDD:275381 18/70 (26%)
AMN1 <602..>653 CDD:187754 22/50 (44%)
leucine-rich repeat 627..652 CDD:275381 10/24 (42%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 1 1.010 - - D1282076at2759
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
21.920

Return to query results.
Submit another query.