Protein Alignment Ppa and Kdm2b

DIOPT Version :9

• Sequence 1: NP_001261138.1
• Gene: Ppa / 37602
• FlyBaseID: FBgn0020257
• Length: 562
• Species: Drosophila melanogaster
• Sequence 2: XP_038945396.1
• Gene: Kdm2b / 304495
• RGDID: 1310217
• Length: 1350
• Species: Rattus norvegicus
• Alignment Length: 353
• Identity: 90/353 - (25%)
• Similarity: 137/353 - (38%)
• Gaps: 85/353 - (24%)

  Fly    79 LRFTPYALHHRPPHHQLQTLPPALYLQHAAAAAAAAAAAAAHAQHHHHHHHHLPHRPASPESPPP 143
            ||..|..:...||    .|.||...                      ....|:...|  |.||||
  Rat  1030 LRSPPRVISRPPP----STSPPKCI----------------------QMERHVIRPP--PISPPP 1066

  Fly   144 VE------GTHISNLFPELLEQIFEHLPVRDLGRAAQVCTAWRDAAYAKSVWKGVEAKLHLKRSS 202
            ..      ..|:  :..|:...:|.:|..:||....:||..|......|.:|..::.. |.|..:
  Rat  1067 DSLPLDDGAAHV--MHREVWMAVFSYLSHQDLCVCMRVCRTWNRWCCDKRLWTRIDLN-HCKSIT 1128

  Fly   203 PSLFNCLVKRGIKKVQILSL--------RRSLKDLVLGVPALTSLNLSGCFNVADMNLGHAFSVD 259
            |.:.:.:::|     |.:||        ::.|..|:..:|.|..|.||||..:|   :....|..
  Rat  1129 PLMLSGIIRR-----QPVSLDLSWTNISKKQLSWLINRLPGLRDLVLSGCSWIA---VSALCSSS 1185

  Fly   260 LPNLKTLDL------------SLCKQITDTSLGRI--AQHLRNLETLELGGCCNITNTGLLLIAW 310
            .|.|:|||:            .|....||...|::  ...|||:..|.|.| .:||:..|.||..
  Rat  1186 CPLLRTLDVQWVEGLKDAQMRDLLSPPTDNRPGQMDNRSKLRNIVELRLAG-LDITDVSLRLIIR 1249

  Fly   311 GLKKLKHLNLRSCWHISDQGIGHLAGFSRETAEGNLQLEYLGLQDCQRLSDEAL------GHIAQ 369
            .:..|..|:|..|.|::||.|..|......|.:   .|..:.|.||.:::|:.|      |:|..
  Rat  1250 HMPLLSKLHLSYCNHVTDQSINLLTAVGTTTRD---SLTEINLSDCNKVTDQCLSFFKRCGNICH 1311

  Fly   370 GLTSLKSINLSFCVSVTDSGLKH-LARM 396
                   |:|.:|..||..|.:. :|.|
  Rat  1312 -------IDLRYCKQVTKEGCEQFIAEM 1332

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ppa	NP_001261138.1	F-box-like	149..190	CDD:289689	9/40 (23%)
		AMN1	<226..>334	CDD:187754	39/121 (32%)
		leucine-rich repeat	236..256	CDD:275381	7/19 (37%)
		leucine-rich repeat	263..288	CDD:275381	9/38 (24%)
		leucine-rich repeat	289..314	CDD:275381	8/24 (33%)
		leucine-rich repeat	315..347	CDD:275381	10/31 (32%)
		AMN1	347..524	CDD:187754	16/57 (28%)
		leucine-rich repeat	348..373	CDD:275381	8/30 (27%)
		leucine-rich repeat	374..398	CDD:275381	8/24 (33%)
		leucine-rich repeat	399..424	CDD:275381
		leucine-rich repeat	425..450	CDD:275381
		leucine-rich repeat	451..475	CDD:275381
		leucine-rich repeat	476..501	CDD:275381
Kdm2b	XP_038945396.1	JmjC	151..226	CDD:214721
		cupin_RmlC-like	198..304	CDD:424065
		JHD	303..>338	CDD:407680
		CTD_KDM2B	476..584	CDD:412026
		zf-CXXC	<626..662	CDD:366873
		PHD_KDM2B	672..733	CDD:277114
		PTZ00449	<731..967	CDD:185628
		F-box-like	1082..1120	CDD:403981	10/37 (27%)
		leucine-rich repeat	1116..1140	CDD:275381	5/29 (17%)
		AMN1	1132..1321	CDD:187754	56/207 (27%)
		leucine-rich repeat	1141..1164	CDD:275381	4/22 (18%)
		leucine-rich repeat	1165..1188	CDD:275381	8/25 (32%)
		leucine-rich repeat	1189..1228	CDD:275381	9/38 (24%)
		leucine-rich repeat	1229..1253	CDD:275381	8/24 (33%)
		leucine-rich repeat	1254..1283	CDD:275381	10/31 (32%)
		leucine-rich repeat	1284..1308	CDD:275381	6/23 (26%)
		leucine-rich repeat	1309..1333	CDD:275381	9/31 (29%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1947
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810