Protein Alignment Ppa and F44E5.2

DIOPT Version :10

• Sequence 1: NP_001261138.1
• Gene: Ppa / 37602
• FlyBaseID: FBgn0020257
• Length: 562
• Species: Drosophila melanogaster
• Sequence 2: NP_496512.2
• Gene: F44E5.2 / 185735
• WormBaseID: WBGene00009689
• Length: 489
• Species: Caenorhabditis elegans
• Alignment Length: 482
• Identity: 106/482 - (21%)
• Similarity: 175/482 - (36%)
• Gaps: 144/482 - (29%)

  Fly   154 PELLEQIFEHLPVRDLGRAAQVC-TAWRDAAYAKSVWKGVEAKLHLKRSSPSLFNCLVKRGIKKV 217
            ||:..|||..|...|:......| ...|.....|:|.|.|..: |:|..|.:....|....|.||
 Worm    29 PEISNQIFTKLVALDIELDPNYCLQISRKLNITKAVCKNVTTE-HIKLLSNNCILSLTIGNIDKV 92

  Fly   218 Q----------ILSLRRSLKDLVLGVPA---LTSLNLSG----CFNVADMNLGHAFSVDLPNLKT 265
            :          |:::.|.|:| |||..:   |..|::.|    .:|.... |||.    ||:|:|
 Worm    93 KQVYQDDKENPIINIARLLED-VLGEESRQNLQYLDIQGNELFSYNWPKA-LGHM----LPSLQT 151

  Fly   266 LDLSLCKQITDTSLGRIAQHLRNLETLELGGCCNITNTGLLLIAWGLKKLKHLNLRSCWHISDQG 330
            |.:.....|.| ...::.....||..|:                                |||..
 Worm   152 LIVCQRSFIND-EFSQLCNSFPNLHKLD--------------------------------ISDTN 183

  Fly   331 IGHLAGFSRETAEGNLQ------LEYLGLQDCQRLSDEALGHIAQGLTSLKSINLS-----FCVS 384
            ||:|:|.|...   |||      ||:....|.:.|.:         :.||:.:|:|     |..|
 Worm   184 IGNLSGISNLK---NLQKLCMMNLEFESYDDIKELFE---------VKSLRVLNISRDRKDFKPS 236

  Fly   385 VTDSGLKHLARMPKLEQLNLRSC-------DNISDI--------GMAYLTEGGSG--------IN 426
            :.   ::::.....|.:|....|       ::||.|        .:|.|.|.|..        :|
 Worm   237 LI---MQYIQLKEVLPELRFLDCSGTNVDKESISTIQNSHPNLKKVAALCEPGKNFIVPEIKILN 298

  Fly   427 SLDVSFCDKISDQ--ALTH---IAQGLYRLRSLSLNQCQITDHGMLKIAKALHELENLNI----G 482
            |:|:....|..:.  .|.|   ::|.|:.|.:...:...|.:..:..:.:|::...:.|:    |
 Worm   299 SIDLGSTLKCLEHYTTLKHDVFMSQCLHALFNFIKSSYHIDNEWIQYVYRAINTCSSDNVQIQGG 363

  Fly   483 QC-------------------SRITDKGLQTLAEDLTNLKTIDLYGCTQLSSKGIDIIMKLPKLQ 528
            .|                   ||:..||  ::|:...|....:.:..|.|..|    ::.|..|:
 Worm   364 ACLSLIVKKSIKTMRPYEVALSRVVCKG--SVAKTFYNASKPNSWDLTVLERK----VVSLEVLK 422

  Fly   529 KLNLGLWLVRXCVHHDCNACAAKEAAR 555
            .:..|:.:...|:   .|....||..|
 Worm   423 PIAYGIIVRDMCM---INILNCKETLR 446

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ppa	NP_001261138.1	F-box_FBXL14	150..190	CDD:438897	11/36 (31%)
		AMN1	<226..>334	CDD:187754	27/114 (24%)
		leucine-rich repeat	236..256	CDD:275381	7/23 (30%)
		leucine-rich repeat	263..288	CDD:275381	5/24 (21%)
		leucine-rich repeat	289..314	CDD:275381	2/24 (8%)
		leucine-rich repeat	315..347	CDD:275381	9/31 (29%)
		AMN1	347..524	CDD:187754	44/238 (18%)
		leucine-rich repeat	348..373	CDD:275381	4/24 (17%)
		leucine-rich repeat	374..398	CDD:275381	5/28 (18%)
		leucine-rich repeat	399..424	CDD:275381	10/39 (26%)
		leucine-rich repeat	425..450	CDD:275381	8/29 (28%)
		leucine-rich repeat	451..475	CDD:275381	3/23 (13%)
		leucine-rich repeat	476..501	CDD:275381	8/47 (17%)
F44E5.2	NP_496512.2	LRR	22..>278	CDD:443914	71/303 (23%)
		leucine-rich repeat	123..148	CDD:275380	8/29 (28%)
		leucine-rich repeat	149..173	CDD:275380	5/24 (21%)
		leucine-rich repeat	174..195	CDD:275380	10/55 (18%)