Protein Alignment Ppa and K02A6.3

DIOPT Version :9

• Sequence 1: NP_001261138.1
• Gene: Ppa / 37602
• FlyBaseID: FBgn0020257
• Length: 562
• Species: Drosophila melanogaster
• Sequence 2: NP_001024745.1
• Gene: K02A6.3 / 181077
• WormBaseID: WBGene00019294
• Length: 483
• Species: Caenorhabditis elegans
• Alignment Length: 508
• Identity: 100/508 - (19%)
• Similarity: 163/508 - (32%)
• Gaps: 192/508 - (37%)

  Fly   155 ELLEQIFEHLPVRDLGRAAQVCTAWRDAAYAKSVWKGVEAKLHLKRSSPSLFNCLVKRGIKKVQI 219
            ||||.||:.|||::.||.:|||..|:         :|..:||..::.:       .:.||
 Worm    13 ELLEDIFQRLPVKNKGRCSQVCRQWQ---------RGFNSKLSWRKFT-------FQDGI----- 56

  Fly   220 LSLRRSLKDLVLGVPALTSLNLSGCFNVADMNLGHAFSVDLPNLKTLDLSLCKQITDTSLGRIAQ 284
             .:||..                      ..:.|..:.:|...||.|       ||:|:     .
 Worm    57 -FVRRKY----------------------TQHSGWQYHIDHWRLKNL-------ITNTT-----S 86

  Fly   285 HLRNLETLELGGCCNITNTGLLLIAWG------------LKKLKHLNLRSCWHI----------- 326
            ..|.|....:....|:.....:|..:.            :.|:...|.:  ||:
 Worm    87 SWRTLNVEPVSNIFNLYEFFRVLANYSEYYEKFSSQDRPMAKIHTFNFK--WHLHVDENETGGFI 149

  Fly   327 --SDQGIGHLAGFSRETAEGNLQ-LEYLGLQDCQRLSDEA-------LGHIAQGLTSLKSINLSF 381
              .|.|.|.....|.:|....|. |:.|.|.|.|...|||       |....:.||.|..:|::.
 Worm   150 AGKDVGTGGQILHSLKTVLNYLHGLKSLSLVDLQLTHDEADDFLSTLLEKFYEKLTYLSLLNVTL 214

  Fly   382 ---------C--------VSVTDSGLKHLARMPKLEQLNLRSCDNISDIGMAYLTEGGSGINSLD 429
                     |        ||........|:.:..||.|...|...::....:......|..:|.
 Worm   215 YPKPLLQVGCFLKLRKLLVSPQMLSTDTLSAIACLEHLETLSIVQVTATPYSLFPPTSSATDSF- 278

  Fly   430 VSFCDKISDQALTHIAQGLYRL---RSLSLNQCQITDHGMLKIAKALH--------ELENLNIGQ 483
             .|.|:.|.|: |.|.:..:.:   :::...:..:...|..|::..:.        ::|| :.||
 Worm   279 -VFQDEKSSQS-TDICRNAWDMFVKQNMDRTRVWLILRGKPKMSLIIQPGAPIYGIKMEN-SAGQ 340

  Fly   484 CSRITDKGLQTLAEDLTNLKTIDLYGCT--------------------QLSSKGIDIIMKLPKLQ 528
            .:       ..|||.:.|     .||.|                    ::.|..|:|:.:.|.|:
 Worm   341 LT-------MELAEQIAN-----YYGATLRHFIQCGLERMKRGKKMEERVDSALIEIVSRCPNLE 393

  Fly   529 KL---------------------NLGLW------LVRXC----------VHHD 544
            :|                     ..|||      |.| |          :|.|
 Worm   394 RLACRERMSYGTAVILSVYAERIGFGLWIRKNALLKRICWCRLDMEAQAIHFD 446

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ppa	NP_001261138.1	F-box-like	149..190	CDD:289689	15/34 (44%)
		AMN1	<226..>334	CDD:187754	19/132 (14%)
		leucine-rich repeat	236..256	CDD:275381	1/19 (5%)
		leucine-rich repeat	263..288	CDD:275381	6/24 (25%)
		leucine-rich repeat	289..314	CDD:275381	3/36 (8%)
		leucine-rich repeat	315..347	CDD:275381	8/44 (18%)
		AMN1	347..524	CDD:187754	45/232 (19%)
		leucine-rich repeat	348..373	CDD:275381	10/31 (32%)
		leucine-rich repeat	374..398	CDD:275381	6/40 (15%)
		leucine-rich repeat	399..424	CDD:275381	4/24 (17%)
		leucine-rich repeat	425..450	CDD:275381	7/24 (29%)
		leucine-rich repeat	451..475	CDD:275381	2/34 (6%)
		leucine-rich repeat	476..501	CDD:275381	7/24 (29%)
K02A6.3	NP_001024745.1	FBOX	10..50	CDD:197608	18/45 (40%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	41	1.000	Domainoid score	I8533
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.000