Protein Alignment Ppa and gadr-6

DIOPT Version :9

• Sequence 1: NP_001261138.1
• Gene: Ppa / 37602
• FlyBaseID: FBgn0020257
• Length: 562
• Species: Drosophila melanogaster
• Sequence 2: NP_493455.1
• Gene: gadr-6 / 173273
• WormBaseID: WBGene00009823
• Length: 710
• Species: Caenorhabditis elegans
• Alignment Length: 435
• Identity: 97/435 - (22%)
• Similarity: 158/435 - (36%)
• Gaps: 134/435 - (30%)

  Fly   104 LQHAAAAAAAAAAAAAHAQHHHHHHHHLPHRPASPESPPPVEGTHISNLFPELLEQIFEHLPVRD 168
            |:|.||||.|...        |:.|.:........||         ||   |:..|:....|
 Worm     5 LKHTAAAAIAKLI--------HNGHFNSKSYAFDQES---------SN---EVYAQLLRLDP--- 46

  Fly   169 LGRAAQVCTAWRDAAYAKSVWKGVEAKLHLKRSSPSLFNCLVKRGIKKVQI------LSLRRSLK 227
                     .|   :|      .::.||      ..|...|.|...:.|::      |..:.:||
 Worm    47 ---------QW---SY------NIDLKL------KGLSFILTKVNFENVEMGPQTFGLLTQHNLK 87

  Fly   228 DLVLG----VPAL---------TS----LNLSG--CFNVADMNLGHAFSVDLPNLKTLDLSLCKQ 273
            .||||    :|:|         ||    |:|||  .|:.|.:.   .....||.|:||::|..|
 Worm    88 SLVLGNQDEIPSLEHYMSRLFRTSQIDHLDLSGRSQFSTAWLK---TTGQQLPLLRTLNVSGVK- 148

  Fly   274 ITDTSLGRIAQHLRNLETLELGGCCNITNTGLLLIAWGLKKLKHLNLRS----CWH-------IS 327
            :.:....:..:...||.:|::..|.....||:.    .||.|:||:|||    .|:       :.
 Worm   149 LLNPDFFQFCKSFPNLYSLDISNCGVTILTGIS----RLKNLRHLSLRSLIYESWYDIRELFALK 209

  Fly   328 DQGIGHLAGFSRETAEGNLQLEYLGLQDCQRLSDEALGHIAQGLTSLKSINLSFCVSVTDSGLKH 392
            ...:..|:..|...|..|:| .:|   ||:::..|.......|  :|...::...:.:|.|.|..
 Worm   210 LLNVLDLSMHSTHHARRNMQ-RFL---DCKQVLPELRFLECSG--NLMDEDMLEELLITHSHLHQ 268

  Fly   393 LA------RMPKLEQLNLRSCDNISDIGMAYLTEGGSGINSLDVSFCDKISDQALTHIAQGLYRL 451
            ||      :.||...:.:.||...                           |.::|.:.   |.|
 Worm   269 LAIVDCDVKAPKSSPIRILSCTTF---------------------------DSSITALK---YYL 303

  Fly   452 RSLSLNQCQITDHGMLKIAKALHELE-NLNIGQCSRITDKGLQTL 495
            .....|:.||....:....|.|||.: ..::.:|..::.:.|:.|
 Worm   304 NLKRRNEVQICFQELRLHVKRLHERKMQYDVTECVTLSLQSLEKL 348

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ppa	NP_001261138.1	F-box-like	149..190	CDD:289689	7/40 (18%)
		AMN1	<226..>334	CDD:187754	38/137 (28%)
		leucine-rich repeat	236..256	CDD:275381	9/34 (26%)
		leucine-rich repeat	263..288	CDD:275381	5/24 (21%)
		leucine-rich repeat	289..314	CDD:275381	6/24 (25%)
		leucine-rich repeat	315..347	CDD:275381	11/42 (26%)
		AMN1	347..524	CDD:187754	30/156 (19%)
		leucine-rich repeat	348..373	CDD:275381	5/24 (21%)
		leucine-rich repeat	374..398	CDD:275381	6/29 (21%)
		leucine-rich repeat	399..424	CDD:275381	2/24 (8%)
		leucine-rich repeat	425..450	CDD:275381	2/24 (8%)
		leucine-rich repeat	451..475	CDD:275381	6/23 (26%)
		leucine-rich repeat	476..501	CDD:275381	3/21 (14%)
gadr-6	NP_493455.1	leucine-rich repeat	86..112	CDD:275381	9/25 (36%)
		leucine-rich repeat	113..138	CDD:275381	7/27 (26%)
		leucine-rich repeat	139..163	CDD:275381	5/24 (21%)
		leucine-rich repeat	164..185	CDD:275381	6/24 (25%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160162698
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.930