Protein Alignment Ppa and FBXO39

DIOPT Version :9

• Sequence 1: NP_001261138.1
• Gene: Ppa / 37602
• FlyBaseID: FBgn0020257
• Length: 562
• Species: Drosophila melanogaster
• Sequence 2: NP_694962.1
• Gene: FBXO39 / 162517
• HGNCID: 28565
• Length: 442
• Species: Homo sapiens
• Alignment Length: 410
• Identity: 83/410 - (20%)
• Similarity: 153/410 - (37%)
• Gaps: 128/410 - (31%)

  Fly   154 PEL-LEQIFEHLPVRDLGRAAQVCTAWRDAAYAKSVWK-------GVEAKLHLKRSSPSLFNCLV 210
            |:| |.::|..|..||..|||.||..|....|:..:|:       |..:::|......:::.
Human    20 PDLCLCRVFWWLGDRDRSRAALVCRKWNQMMYSAELWRYRTITFSGRPSRVHASEVESAVWY--- 81

  Fly   211 KRGIKKVQILSLRRSLKDLVLGVPALTSLNLSGCFNVADMNLGHAFSVDLPNLKTLDLSLCKQIT 275
               :||     ..|.|:.|                .|..||..:|.             |.|:..
Human    82 ---VKK-----FGRYLEHL----------------EVKFMNPYNAV-------------LTKKFQ 109

  Fly   276 DTSLGRIAQHLRNLETLELGGCCNITNTGLLLIAWGLKKLKHLNL-RSCWH--ISDQGIGHLAGF 337
            .|..|.::             |.:.:|..|..::     :::|.| |..|.  |....|..|:.|
Human   110 VTMRGLLS-------------CLSKSNNRLKSLS-----IQYLELDRLVWRNSIRSSFISSLSFF 156

  Fly   338 SRETAEGNLQLEYLGLQDCQRLSDEALGHIAQGLTSLKSINLSFCVSVTDSGLKHLA--RMPKLE 400
            .::..:   :|:||.|:.. ||:.|....|...|:.:::.|:...:::.|....|||  ..|:.:
Human   157 LKKMGK---RLDYLNLKGA-RLTVEQGCQILDSLSYMRNENVISELNIEDYFSHHLAVYNSPQFK 217

  Fly   401 QLNLRSCDNISDIGMAYLTEGGSGINSLDVSFCDKISDQALTHIAQGLYRLRSLSLNQCQITD-H 464
            : .:.:..|:..:.:.|                :.|||:.|.::.:....||:::: :|.:.| |
Human   218 K-TMSTFHNLVSLNLNY----------------NCISDELLENLCENASTLRTINI-KCHVHDPH 264

  Fly   465 GMLKIAKALHELENLNIGQCSRITDKGLQTLAEDLTNLKTIDLYGCTQLSSKGIDIIMKLPK--- 526
            |.:                   |.......||...|||| ::.:         .:.|||..:
Human   265 GQV-------------------IWGMSWAKLARQATNLK-VNFF---------FERIMKYERLAR 300

  Fly   527 --LQKLNLGLWLVRXCVHHD 544
              ||::.:....:| |...|
Human   301 ILLQEIPIRSISLRSCYFSD 320

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ppa	NP_001261138.1	F-box-like	149..190	CDD:289689	14/36 (39%)
		AMN1	<226..>334	CDD:187754	19/110 (17%)
		leucine-rich repeat	236..256	CDD:275381	3/19 (16%)
		leucine-rich repeat	263..288	CDD:275381	4/24 (17%)
		leucine-rich repeat	289..314	CDD:275381	3/24 (13%)
		leucine-rich repeat	315..347	CDD:275381	8/34 (24%)
		AMN1	347..524	CDD:187754	36/179 (20%)
		leucine-rich repeat	348..373	CDD:275381	9/24 (38%)
		leucine-rich repeat	374..398	CDD:275381	5/25 (20%)
		leucine-rich repeat	399..424	CDD:275381	2/24 (8%)
		leucine-rich repeat	425..450	CDD:275381	4/24 (17%)
		leucine-rich repeat	451..475	CDD:275381	6/24 (25%)
		leucine-rich repeat	476..501	CDD:275381	3/24 (13%)
FBXO39	NP_694962.1	F-box-like	16..57	CDD:289689	14/36 (39%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1947
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.900