Protein Alignment Ppa and AgaP_AGAP006431

DIOPT Version :9

• Sequence 1: NP_001261138.1
• Gene: Ppa / 37602
• FlyBaseID: FBgn0020257
• Length: 562
• Species: Drosophila melanogaster
• Sequence 2: XP_316467.3
• Gene: AgaP_AGAP006431 / 1277041
• VectorBaseID: AGAP006431
• Length: 680
• Species: Anopheles gambiae
• Alignment Length: 615
• Identity: 120/615 - (19%)
• Similarity: 216/615 - (35%)
• Gaps: 170/615 - (27%)

  Fly    26 GGSG--SNGAATSGGAAIGG--------------------AGAGGAPSWAMDELYQQTELPGLTR 68
            ||.|  |..||.:..||.||                    |.:||.|....|...:..:..|..:
Mosquito    80 GGQGAASTSAAVAVAAAAGGKEQSTGQTPSVSNGASLPRVASSGGKPKAMRDFDRKMNKSRGRPK 144

  Fly    69 TGATTTHHH-------------LLRFTPYALHHRPPHHQLQTLPPALYLQHAAAAAAAAAAAAAH 120
            ..|....:.             :.:.:...:..:.|..:....|.:|....:...:.........
Mosquito   145 RKAMVAMYQSQISENKIGIKLCIKKASDATVQPKKPIRKRARKPRSLNEDSSDETSPEKRNRRTE 209

  Fly   121 AQHHHHHHHHLPHRPASPESPPPVEGTHISNLFPE-LLEQIFEH-------LPVRDLGRAAQVCT 177
            .......:::...|.|......|.:.:..:|..|| :|..||::       ||.  |.|.::||.
Mosquito   210 KPRPKKTNNNTEKRSAEEAYTSPKDQSVWANGLPESVLYTIFKNAVQEEGCLPT--LIRLSEVCM 272

  Fly   178 AWRDAAYAKSVWKGVEAKLHLK---RSSPSLFNCLVKR-------GIKKVQILSLRRSLKDLVLG 232
            ||...:...|:|:.|:.....:   ::.|.|...:..|       |:...::.:::..|..|:..
Mosquito   273 AWYKVSQQCSLWRTVDLGTWGRDRFKTEPRLKWLIENRLQHATEVGLANWKVTNVQCVLDKLLEA 337

  Fly   233 VPALTSLNLSGCFNVADMNLGHAFSV-DLPNLKTLDL-----------------SLCKQITDTS- 278
            .|.||:::|:|...::..:|  .|.| :..:|:.|||                 |||..|.:..
Mosquito   338 APGLTTISLAGWKALSTDHL--MFLVQNFKSLRNLDLSSVNAEVNANKTAVGQTSLCNAIKEMGS 400

  Fly   279 ------------------LGRIAQHLRNLETLELGGCCNIT-NTGLLLI---AWGLKKLKHLNLR 321
                              :..:|.|..||..|:|.....:. :.|:|.|   ..|.:|||.|.:.
Mosquito   401 RLTHLHLAHNRLSGIPQIVKALATHCPNLLLLDLSNVNTVAMSHGILHIEQLQHGCQKLKVLRIT 465

  Fly   322 SCWHISDQGIGHLAGFSRETAEGNLQLEYLGLQDCQRLS------------DEALGHIAQGLTSL 374
            :. ||           :..||....|:|..|..:.:.||            ||.|..|.:..|.|
Mosquito   466 NS-HI-----------NLSTASLQEQMESPGFPELEELSVASLADEARLFNDEFLQRILKTSTKL 518

  Fly   375 KSINLSFCVSVT-DSGLKHLARMP--KLEQLNLRSCDNISDIG---------------------- 414
            ..:::..|..:| ||    |.|:|  .|:.|.|..|....|:|
Mosquito   519 TLLDVRGCARLTHDS----LIRLPTWDLKHLFLSGCSINRDMGAGLELIASKWAHSLIEFDLAWA 579

  Fly   415 ---------MAYLTEGGSGINSLDVSFC-DKISDQALTHIAQGLYRLRSLSLNQCQITDHGMLKI 469
                     :..|.:.||......::.| ..:|.:|:..:......:.:::|..|:....|:.::
Mosquito   580 SATKPLDDALKALADKGSESPLKYLNLCGSSVSLEAVKEVLANCPHINAINLASCRGLPRGVKRL 644

  Fly   470 AKALHELENL--NIG---QCSRITDKGLQT 494
            .:...|:..|  |:|   :|:    .|:|:
Mosquito   645 LQGAQEIAELRENLGVTLKCA----PGVQS 670

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ppa	NP_001261138.1	F-box-like	149..190	CDD:289689	15/48 (31%)
		AMN1	<226..>334	CDD:187754	34/148 (23%)
		leucine-rich repeat	236..256	CDD:275381	5/19 (26%)
		leucine-rich repeat	263..288	CDD:275381	10/60 (17%)
		leucine-rich repeat	289..314	CDD:275381	7/28 (25%)
		leucine-rich repeat	315..347	CDD:275381	7/31 (23%)
		AMN1	347..524	CDD:187754	40/200 (20%)
		leucine-rich repeat	348..373	CDD:275381	8/36 (22%)
		leucine-rich repeat	374..398	CDD:275381	8/26 (31%)
		leucine-rich repeat	399..424	CDD:275381	8/55 (15%)
		leucine-rich repeat	425..450	CDD:275381	3/25 (12%)
		leucine-rich repeat	451..475	CDD:275381	3/23 (13%)
		leucine-rich repeat	476..501	CDD:275381	6/24 (25%)
AgaP_AGAP006431	XP_316467.3	DUF4544	<156..243	CDD:291736	7/86 (8%)
		F-box-like	242..289	CDD:289689	16/48 (33%)
		leucine-rich repeat	341..366	CDD:275381	7/26 (27%)
		leucine-rich repeat	402..428	CDD:275381	2/25 (8%)
		leucine-rich repeat	429..458	CDD:275381	7/28 (25%)
		leucine-rich repeat	459..487	CDD:275381	10/39 (26%)
		leucine-rich repeat	488..517	CDD:275381	6/28 (21%)
		leucine-rich repeat	518..541	CDD:275381	8/26 (31%)
		leucine-rich repeat	542..598	CDD:275381	8/55 (15%)
		leucine-rich repeat	601..625	CDD:275381	3/23 (13%)
		leucine-rich repeat	626..647	CDD:275381	3/20 (15%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1947
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810