DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ppa and AgaP_AGAP004478

DIOPT Version :9

Sequence 1:	NP_001261138.1	Gene:	Ppa / 37602	FlyBaseID:	FBgn0020257	Length:	562	Species:	Drosophila melanogaster
Sequence 2:	XP_313777.5	Gene:	AgaP_AGAP004478 / 1274626	VectorBaseID:	AGAP004478	Length:	197	Species:	Anopheles gambiae

Alignment Length:	90	Identity:	28/90 - (31%)
Similarity:	52/90 - (57%)	Gaps:	6/90 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly   327 SDQGIGHLAGFSRETAEGNLQLEYLGLQDCQRLSDEALGHIAQGLTSLKSINLSFCVSVTDSGLK 391
            :|.||.|: ||  :..||..:|..:.|.:|..:.::||..:.....:|:.:.:|.|.:|||:||.
Mosquito    94 TDSGIMHI-GF--DHLEGLSRLRKVVLHNCVYIDNQALWKLRYVANTLEELQISKCGNVTDAGLL 155

  Fly   392 HLARMPKLEQL---NLRSCDNISDI 413
            .|.::|:|:|:   :|....||.::
Mosquito   156 QLKQLPQLQQVKTFDLPDVKNIQEV 180

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ppa	NP_001261138.1	F-box-like	149..190	CDD:289689
		AMN1	<226..>334	CDD:187754	3/6 (50%)
		leucine-rich repeat	236..256	CDD:275381
		leucine-rich repeat	263..288	CDD:275381
		leucine-rich repeat	289..314	CDD:275381
		leucine-rich repeat	315..347	CDD:275381	8/19 (42%)
		AMN1	347..524	CDD:187754	20/70 (29%)
		leucine-rich repeat	348..373	CDD:275381	5/24 (21%)
		leucine-rich repeat	374..398	CDD:275381	9/23 (39%)
		leucine-rich repeat	399..424	CDD:275381	5/18 (28%)
		leucine-rich repeat	425..450	CDD:275381
		leucine-rich repeat	451..475	CDD:275381
		leucine-rich repeat	476..501	CDD:275381
AgaP_AGAP004478	XP_313777.5	leucine-rich repeat	112..137	CDD:275381	5/24 (21%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910