DRSC/TRiP Functional Genomics Resources

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Protein Alignment Ppa and AgaP_AGAP005297

DIOPT Version :9

Sequence 1:NP_001261138.1 Gene:Ppa / 37602 FlyBaseID:FBgn0020257 Length:562 Species:Drosophila melanogaster
Sequence 2:XP_309088.3 Gene:AgaP_AGAP005297 / 1270388 VectorBaseID:AGAP005297 Length:392 Species:Anopheles gambiae


Alignment Length:384 Identity:102/384 - (26%)
Similarity:156/384 - (40%) Gaps:78/384 - (20%)


- Green bases have known domain annotations that are detailed below.


  Fly    90 PPHH------QLQTLPPALYLQHAAAAAAAAAAAAAHAQHHHHHHHHLPHRPASPESPPPVEGTH 148
            ||||      ||:..|                    |........:....|.|:..     |...
Mosquito    30 PPHHDPLSEEQLKYAP--------------------HGSEEAFFMYRKNQRKATYG-----EEDL 69

  Fly   149 ISNLFPELLEQIFEHLPVRDLGRAAQVCTAWRDAAYAKSVWKGVEAKLHLKRSSPSL-FNCLVK- 211
            .|.|..|:|..|.:.||.:.|....||...:...:..:::|      ..|..|:.:| |:.||: 
Mosquito    70 FSLLSDEVLLHILKWLPKKTLLSCGQVNRRFNRVSKDETLW------YRLDLSNRTLQFDGLVEV 128

  Fly   212 --RGIKKVQILSLRRSLKDLVLGVPALTSLNLSGCFNVADMNLGHAFSVDLPNLKTLDLSLCKQI 274
              ||     ::.||.:...:|...|....|....|..|..::|... :|.|..|..| |:.|:.:
Mosquito   129 LSRG-----VIVLRLAQTSIVNPTPDSNYLEFPACIKVQYLDLSMC-TVSLAVLGAL-LANCRAL 186

  Fly   275 TDTSL------GRIAQHL---RNLETLELGGCCNITNTGLLLIAWGLKKLKHLNLRSCWHISDQG 330
            ...||      |||...:   |.||.|.|..|..|..||:.|:|..|.:|..||: |...:|.:.
Mosquito   187 VKLSLENVPLDGRICAEIAENRKLEALNLTMCSGIDATGMRLMAKALTRLHSLNV-SWTSLSAEA 250

  Fly   331 IGHLAGFSRETAEGNL--QLEYLGLQDCQ-RLSDEALGHIAQGLTSLKSINLSFCVSVTDSGLKH 392
            :..|.        .||  |:.:|.|..|: .|:||.:..:.:..|.|.:::||.|..:|:..:|.
Mosquito   251 VQELV--------RNLTPQIVHLNLSGCRSTLTDEKVAVLIKRCTKLVALDLSDCTPLTEVVIKT 307

  Fly   393 LARMPKLEQLNLRSCDNISDIGMAYLTEGGSGINSLDVSFCD---KISDQALTHIAQGL 448
            |.:..|:|.|:|..|.||.......|||    :.:|  .|.|   .:||||:..:...|
Mosquito   308 LCKARKIEYLSLSRCYNIPVTAYLNLTE----LKTL--RFLDLFGLVSDQAIATLKNSL 360

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
PpaNP_001261138.1 F-box-like 149..190 CDD:289689 10/40 (25%)
AMN1 <226..>334 CDD:187754 34/116 (29%)
leucine-rich repeat 236..256 CDD:275381 4/19 (21%)
leucine-rich repeat 263..288 CDD:275381 9/33 (27%)
leucine-rich repeat 289..314 CDD:275381 11/24 (46%)
leucine-rich repeat 315..347 CDD:275381 8/33 (24%)
AMN1 347..524 CDD:187754 33/106 (31%)
leucine-rich repeat 348..373 CDD:275381 6/25 (24%)
leucine-rich repeat 374..398 CDD:275381 7/23 (30%)
leucine-rich repeat 399..424 CDD:275381 9/24 (38%)
leucine-rich repeat 425..450 CDD:275381 8/27 (30%)
leucine-rich repeat 451..475 CDD:275381
leucine-rich repeat 476..501 CDD:275381
AgaP_AGAP005297XP_309088.3 F-box-like 70..116 CDD:289689 12/51 (24%)
leucine-rich repeat 133..160 CDD:275381 6/26 (23%)
AMN1 148..303 CDD:187754 49/165 (30%)
leucine-rich repeat 161..185 CDD:275381 8/25 (32%)
leucine-rich repeat 186..209 CDD:275381 5/22 (23%)
leucine-rich repeat 210..235 CDD:275381 11/24 (46%)
leucine-rich repeat 236..261 CDD:275381 8/33 (24%)
leucine-rich repeat 262..288 CDD:275381 6/25 (24%)
leucine-rich repeat 289..313 CDD:275381 7/23 (30%)
leucine-rich repeat 314..333 CDD:275381 6/18 (33%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
SonicParanoid 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.910

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