DRSC/TRiP Functional Genomics Resources

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Protein Alignment Ppa and lingo1

DIOPT Version :9

Sequence 1:NP_001261138.1 Gene:Ppa / 37602 FlyBaseID:FBgn0020257 Length:562 Species:Drosophila melanogaster
Sequence 2:NP_001093719.1 Gene:lingo1 / 100101739 XenbaseID:XB-GENE-921957 Length:606 Species:Xenopus tropicalis


Alignment Length:363 Identity:89/363 - (24%)
Similarity:129/363 - (35%) Gaps:119/363 - (32%)


- Green bases have known domain annotations that are detailed below.


  Fly   203 PSLFNCLVKRGIKKVQILSLRRS-LKDLVLGVPALTSLNLSGCFNVADMNLGHAFSVDLPNLKTL 266
            |..||     |:..::.|.||.: ||.:.|||       .:|                |.||..|
 Frog    98 PGAFN-----GLFNLRSLGLRSNRLKLIPLGV-------FTG----------------LSNLTQL 134

  Fly   267 DLSLCKQITDTSLGRIAQHLRNLETLELGGCCNITNTGLLLIAW----GLKKLKHLNLRSCWHIS 327
            |:|..|.:  ..|..:.|.|.||::||:|      :..|:.|:.    ||..|:.|.|..|    
 Frog   135 DISENKIV--ILLDDMFQDLYNLKSLEVG------DNDLVYISHRAFRGLNSLEELTLEKC---- 187

  Fly   328 DQGIGHLAGFSRETAEGNLQLEYLGLQDCQRLSDEALGHIAQGLTSLKSINLSFCVSVTDSGLKH 392
                             ||          ..:..|||.|: .||.:||...|:..| :.|...|.
 Frog   188 -----------------NL----------TSVPTEALSHL-HGLITLKLRYLNINV-IRDYSFKR 223

  Fly   393 LARMPKLEQLNLRSCDNISDIGMAYLTEGGSGINSLDV--SFCDKISDQALTHIAQGLYRLRSLS 455
            |.|:..||..:....|.::..|:.     |..:.||.:  |....|...|:.|:.  ..|..:||
 Frog   224 LYRLKNLEIAHWPYLDTMTSNGLY-----GLNLTSLSITHSNLSSIPYVAIRHLV--YLRFLNLS 281

  Fly   456 LNQCQITDHGMLKIAKALHELENLNIGQCS----------------RITDKGLQTLAE----DLT 500
            .|.....:..||.....|.|. :|..||.|                .::...|.||.|    .:.
 Frog   282 YNPITAVEGSMLYELLRLQEF-HLVGGQLSVVEPYAFRGLNHLKVLNVSSNYLSTLEESSFHSVG 345

  Fly   501 NLKTIDLYGCTQLSSKGIDIIMKLPKLQKLNLGLWLVR 538
            ||:|:              |:.|.|......| ||:.|
 Frog   346 NLETL--------------ILDKNPLACDCRL-LWIFR 368

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
PpaNP_001261138.1 F-box-like 149..190 CDD:289689
AMN1 <226..>334 CDD:187754 29/111 (26%)
leucine-rich repeat 236..256 CDD:275381 1/19 (5%)
leucine-rich repeat 263..288 CDD:275381 8/24 (33%)
leucine-rich repeat 289..314 CDD:275381 8/28 (29%)
leucine-rich repeat 315..347 CDD:275381 5/31 (16%)
AMN1 347..524 CDD:187754 45/198 (23%)
leucine-rich repeat 348..373 CDD:275381 6/24 (25%)
leucine-rich repeat 374..398 CDD:275381 8/23 (35%)
leucine-rich repeat 399..424 CDD:275381 5/24 (21%)
leucine-rich repeat 425..450 CDD:275381 6/26 (23%)
leucine-rich repeat 451..475 CDD:275381 6/23 (26%)
leucine-rich repeat 476..501 CDD:275381 8/44 (18%)
lingo1NP_001093719.1 LRRNT 27..61 CDD:214470
LRR 1 58..79
leucine-rich repeat 59..82 CDD:275380
PLN00113 62..>381 CDD:215061 89/363 (25%)
LRR 2 82..103 3/9 (33%)
leucine-rich repeat 83..106 CDD:275380 4/12 (33%)
LRR_8 106..165 CDD:338972 24/89 (27%)
LRR 3 106..127 8/27 (30%)
leucine-rich repeat 107..130 CDD:275380 10/45 (22%)
LRR 4 130..151 7/22 (32%)
leucine-rich repeat 131..154 CDD:275380 8/24 (33%)
LRR 5 154..175 7/26 (27%)
leucine-rich repeat 155..178 CDD:275380 8/28 (29%)
LRR 6 178..199 9/51 (18%)
leucine-rich repeat 179..250 CDD:275380 25/108 (23%)
LRR 7 202..223 7/21 (33%)
leucine-rich repeat 203..226 CDD:275380 8/23 (35%)
LRR 8 250..271 5/20 (25%)
leucine-rich repeat 251..274 CDD:275380 6/24 (25%)
LRR 9 274..295 6/20 (30%)
leucine-rich repeat 275..298 CDD:275380 6/22 (27%)
LRR 10 298..319 6/21 (29%)
leucine-rich repeat 299..322 CDD:275380 6/23 (26%)
LRR 11 322..343 4/20 (20%)
leucine-rich repeat 323..343 CDD:275380 4/19 (21%)
Ig 425..500 CDD:386229
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.910

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