DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG4250 and LITAF

DIOPT Version :9

Sequence 1:	NP_001246468.1	Gene:	CG4250 / 37599	FlyBaseID:	FBgn0034761	Length:	134	Species:	Drosophila melanogaster
Sequence 2:	XP_011521056.1	Gene:	LITAF / 9516	HGNCID:	16841	Length:	191	Species:	Homo sapiens

Alignment Length:	146	Identity:	44/146 - (30%)
Similarity:	60/146 - (41%)	Gaps:	28/146 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly    14 APGFQAPPSYDSA-------PQQVYPQLHQGQGVIL----QGENTENYES----IGNNAP----- 58
            ||  .|||||:..       |....|......|::.    :|.|..:|.:    |.||.|
Human    46 AP--SAPPSYEETVAVNSYYPTPPAPMPGPTTGLVTGPDGKGMNPPSYYTQPAPIPNNNPITVQT 108

  Fly    59 -----PNVLGQCPSVATCPSCGVRRETKVEFEPSTKTHLLALLICMLGGIC-CCCIPYCTDSCQS 117
                 |......|....||||.....:::.:.....|.|....:|:||.|. ||.||:|.|:.|.
Human   109 VYVQHPITFLDRPIQMCCPSCNKMIVSQLSYNAGALTWLSCGSLCLLGCIAGCCFIPFCVDALQD 173

  Fly   118 AKHTCTSCGAYVGTYK 133
            ..|.|.:|.|.:||||
Human   174 VDHYCPNCRALLGTYK 189

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4250	NP_001246468.1	zf-LITAF-like	66..133	CDD:287559	24/67 (36%)
LITAF	XP_011521056.1	zf-LITAF-like	121..189	CDD:287559	24/67 (36%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165145597
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1564782at2759
OrthoFinder	1	1.000	-	-		FOG0000358
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100529
Panther	1	1.100	-	-	O	PTHR23292
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R4048
SonicParanoid	1	1.000	-	-		X238
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	8	7.880