DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG4250 and litaf

DIOPT Version :9

Sequence 1:NP_001246468.1 Gene:CG4250 / 37599 FlyBaseID:FBgn0034761 Length:134 Species:Drosophila melanogaster
Sequence 2:NP_001002184.1 Gene:litaf / 431731 ZFINID:ZDB-GENE-040704-23 Length:163 Species:Danio rerio


Alignment Length:165 Identity:44/165 - (26%)
Similarity:59/165 - (35%) Gaps:52/165 - (31%)


- Green bases have known domain annotations that are detailed below.


  Fly    12 PQAP--------GFQAPPSYD---------------------SAP--------QQVYPQLHQGQG 39
            |.||        |...|||||                     |.|        .|:||...|||.
Zfish     6 PTAPPMENTTLVGHPPPPSYDEISGANPYYPAGPYPPADMKASGPPPYPTQEYNQMYPPTAQGQP 70

  Fly    40 VILQGENTENYESIGN--NAPPNVLGQCPSVATCPSCGVRRETKVEFEPSTKTHL----LALLIC 98
            |      |....::..  ..|..|.|..|..|.||.|.....|::|:.......|    ||:..|
Zfish    71 V------TSPVVAVQTVYVQPGLVFGNVPVQAHCPVCSQSVITRLEYSSGPLVWLSCAGLAVFGC 129

  Fly    99 MLGGICCCCIPYCTDSCQSAKHTCTSCGAYVGTYK 133
            :.|   ||.||:|.:..:...|.|.:|.:.:|.:|
Zfish   130 IYG---CCLIPFCIEDLKDVTHHCPNCSSVLGVHK 161

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG4250NP_001246468.1 zf-LITAF-like 66..133 CDD:287559 21/70 (30%)
litafNP_001002184.1 Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 1..23 4/16 (25%)
PPxY motif. /evidence=ECO:0000250|UniProtKB:Q99732 22..25 2/2 (100%)
zf-LITAF-like 93..161 CDD:287559 21/70 (30%)
Membrane-binding amphipathic helix. /evidence=ECO:0000305 116..136 7/22 (32%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 1 0.930 - - C170578964
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 1 1.010 - - D1564782at2759
OrthoFinder 1 1.000 - - FOG0000358
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 1 0.900 - - OOG6_100529
Panther 1 1.100 - - O PTHR23292
Phylome 1 0.910 - -
RoundUp 1 1.030 - avgDist Average_Evolutionary_Distance R4048
SonicParanoid 1 1.000 - - X238
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
ZFIN 00.000 Not matched by this tool.
87.880

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