DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG4250 and litaf

DIOPT Version :9

Sequence 1:NP_001246468.1 Gene:CG4250 / 37599 FlyBaseID:FBgn0034761 Length:134 Species:Drosophila melanogaster
Sequence 2:NP_988970.1 Gene:litaf / 394567 XenbaseID:XB-GENE-1017030 Length:148 Species:Xenopus tropicalis


Alignment Length:159 Identity:50/159 - (31%)
Similarity:65/159 - (40%) Gaps:52/159 - (32%)


- Green bases have known domain annotations that are detailed below.


  Fly     9 NMQPQAPGF---QAPPSYDSAP--QQVYPQLHQGQGVILQGENTENYESIGNNAPPNVLGQCP-- 66
            |.||...||   .|||||:.|.  ...||.||||    :..:|..|        ||.::...|  
 Frog     6 NYQPVPIGFTVPSAPPSYEEATFHHPPYPPLHQG----MDAKNMSN--------PPYIVQPVPMQ 58

  Fly    67 ---SVAT-----------------CPSCGVRRETKVEFEPSTKTHLLALLICMLGGIC------- 104
               :|.|                 |.||.....|::|:....    ||.|.|  ||:|       
 Frog    59 PPVTVQTVYVQQAMTLYDRPVQMCCRSCNSMITTRLEYSSGA----LAWLSC--GGLCLLGCIGG 117

  Fly   105 CCCIPYCTDSCQSAKHTCTSCGAYVGTYK 133
            ||.||:|.||.:...|.|.:|.|.:|:||
 Frog   118 CCLIPFCIDSLKDVDHYCPNCHALLGSYK 146

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG4250NP_001246468.1 zf-LITAF-like 66..133 CDD:287559 27/95 (28%)
litafNP_988970.1 PPxY motif. /evidence=ECO:0000250|UniProtKB:Q99732 20..23 2/2 (100%)
zf-LITAF-like 78..146 CDD:371158 24/73 (33%)
Membrane-binding amphipathic helix. /evidence=ECO:0000305 101..123 10/23 (43%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 1 1.010 - - D1564782at2759
OrthoFinder 1 1.000 - - FOG0000358
OrthoInspector 00.000 Not matched by this tool.
Panther 1 1.100 - - O PTHR23292
Phylome 1 0.910 - -
RoundUp 1 1.030 - avgDist Average_Evolutionary_Distance R4048
SonicParanoid 1 1.000 - - X238
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
66.050

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