Protein Alignment Cyp6d2 and ERG11

DIOPT Version :9

• Sequence 1: NP_611698.1
• Gene: Cyp6d2 / 37594
• FlyBaseID: FBgn0034756
• Length: 512
• Species: Drosophila melanogaster
• Sequence 2: NP_011871.1
• Gene: ERG11 / 856398
• SGDID: S000001049
• Length: 530
• Species: Saccharomyces cerevisiae
• Alignment Length: 438
• Identity: 102/438 - (23%)
• Similarity: 178/438 - (40%)
• Gaps: 107/438 - (24%)

  Fly    65 GKIVGIYMLNKRSILIRDAQLARQIMTSDFASFHDRGVYVDEDKDPLSANLFNLRGASWRNLRQK 129
            |:::.:|:..|....:.:|:||                  |...:...|:|
Yeast    97 GRVMTVYLGPKGHEFVFNAKLA------------------DVSAEAAYAHL-------------- 129

  Fly   130 LTPSFSSGKIKGMFGTIDDVGDKLVQH---LEGALDQSDEVEIKDVMTTYAVDIIGSVIFGLEID 191
            .||.|..|.|      .|....:|::.   ::|||       .|:...:| |.:|...::    .
Yeast   130 TTPVFGKGVI------YDCPNSRLMEQKKFVKGAL-------TKEAFKSY-VPLIAEEVY----K 176

  Fly   192 SFRNPKNEFREISSSTSRDESLLLKIHNMSMFICPPIAKLMNRLGYESR--------ILTSLRDM 248
            .||:.|| || ::..|:....:::....|::|...     .:.||.|.|        .|.|..|.
Yeast   177 YFRDSKN-FR-LNERTTGTIDVMVTQPEMTIFTAS-----RSLLGKEMRAKLDTDFAYLYSDLDK 234

  Fly   249 MKRTIEF-----------REEH--NVVRKDMLQLLIRLRNTGKIGEDD--DQVWDMETAQEQLKS 298
            ....|.|           :.:|  ..:....:.|:...|....|.:.|  |.:....|.::.:|
Yeast   235 GFTPINFVFPNLPLEHYRKRDHAQKAISGTYMSLIKERRKNNDIQDRDLIDSLMKNSTYKDGVK- 298

  Fly   299 MSIEKIAAQAFLFYVAGSESTAAASAFTLYELSMYPELLKEAQEEVDAVLMKHNLKPKDRFTYEA 363
            |:.::||.......:.|..::||.||:.|..|:..|::.:|..||...||.    ..|...||:.
Yeast   299 MTDQEIANLLIGVLMGGQHTSAATSAWILLHLAERPDVQQELYEEQMRVLD----GGKKELTYDL 359

  Fly   364 VQDLKFLDICIMETIRKYPGLPFLNRECTEDYPVPGTNHIIAKGTPILISL-FGMQRDPVYFPNP 427
            :|::..|:..|.||:|.:..|..|.|:..:|..||.|:::|..|..:|:|. :...||. ||||.
Yeast   360 LQEMPLLNQTIKETLRMHHPLHSLFRKVMKDMHVPNTSYVIPAGYHVLVSPGYTHLRDE-YFPNA 423

  Fly   428 NGYDPHRFDSNN---------MNYDQAA--------YMPFGEGPRHCI 458
            :.::.||::.::         ::|...|        |:|||.|...||
Yeast   424 HQFNIHRWNKDSASSYSVGEEVDYGFGAISKGVSSPYLPFGGGRHRCI 471

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp6d2	NP_611698.1	p450	65..506	CDD:278495	102/438 (23%)
ERG11	NP_011871.1	CYP51-like	83..521	CDD:410668	102/438 (23%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	103	1.000	Domainoid score	I1492
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	97	1.000	Inparanoid score	I1477
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.050