DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Cyp6d2 and CYP81D7

DIOPT Version :9

Sequence 1:	NP_611698.1	Gene:	Cyp6d2 / 37594	FlyBaseID:	FBgn0034756	Length:	512	Species:	Drosophila melanogaster
Sequence 2:	NP_179900.1	Gene:	CYP81D7 / 816851	AraportID:	AT2G23190	Length:	543	Species:	Arabidopsis thaliana

Alignment Length:	560	Identity:	115/560 - (20%)
Similarity:	220/560 - (39%)	Gaps:	135/560 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MWTILLTILIAGLLY-----RYVKRHYTHWQRLGVDEEPAK-IPF---------GVMDTVMKQER 50
            |.|..|.:.:|.|.:     .:.|||    .:..:...||: :||         .:..|.:...:
plant    45 METHFLILSLAFLFFISLKLLFGKRH----SKFNLPPSPARPLPFIGHLHLLKQPLHRTFLSFSQ 105

  Fly    51 SLGMALADIYARHEGKIVGIYMLNKRSILIRDAQLARQIMTSDFASFHDR-----GVYVDEDKDP 110
            |||          :..|..:.:.|..::::....:|.:..|.:.....:|     |.:::.:...
plant   106 SLG----------DAPIFSLRLGNHLTVVVSSYSIAEECFTKNDIVLANRPKFILGKHIEYNFTT 160

  Fly   111 LSANLFNLRGASWRNLRQKLT-PSFSSGKIKGMFGTIDDVGDKLVQHLEGALDQSDE-----VEI 169
            :::..:   |..|||||:..| ..|||.|:.|......|.    ::||...|.::.:     ||:
plant   161 MTSAPY---GDHWRNLRRIGTLEIFSSHKLNGFLSVRKDE----IRHLLLRLSKNSQHGFAKVEM 218

  Fly   170 KDVMTTYAVDIIGSVIFGLEIDSFRNPKNEFREISSSTSRDESLLLKIHNMSMFICPPIAKLMNR 234
            :.:.....::.|..::.|.            |.....|.:||            :...:.:|::.
plant   219 RQLFYDLTINNILRMVAGK------------RFYGEGTEQDE------------VARRVTQLIDE 259

  Fly   235 LGYES------------RILT----SLRDMMKRTIEF-------REEHNVVRKDMLQLLIRLRNT 276
            :.|.:            |.:|    .::::..|..||       |..|......|:..|:.|:.|
plant   260 IVYRAGVGNAADYIPILRWITDFEKGVKELASRVDEFLQSLVDERRVHKQKGNTMMDHLLSLQET 324

  Fly   277 GKIGEDDDQVWDMETAQEQLKSMSIEKIAAQAFLFYVAGSESTAAASAFTLYELSMYPELLKEAQ 341
                 ..|...|:     .||.:.|..|        :||:|:.|....:.:..|..:||:|::|:
plant   325 -----QPDYYTDV-----TLKGIIIVMI--------LAGTETLAGTLEWAMLNLLNHPEVLEKAR 371

  Fly   342 EEVDAVLMKHNLKPKDRFTYEA-VQDLKFLDICIMETIRKYPGLPFLNRECTED------YPVPG 399
            .|:|..:      ..||...|| .::|.:|...::||:|.||..|......|.|      |.||
plant   372 TEIDTEV------GFDRLMDEADTKNLPYLQWIVLETLRLYPVAPTNIPHMTSDDCILAGYDVP- 429

  Fly   400 TNHIIAKGTPILISLFGMQRDPVYFPNPNGYDPHRFDSNNMNYDQAAYMPFGEGPRHCIALRMGK 464
                  :|:.:|::::.|.|||..:..|..:.|.||.:..:|   ...:.||.|.|.|..:.:..
plant   430 ------RGSMLLVNVWSMHRDPSIWEAPEMFKPERFKNEKLN---QKLLSFGFGRRACPGVGLAH 485

  Fly   465 VNSKVAVAKILANFDLVQSPRKEVEFRFDAAPVLVTKEPL 504
            ....:|:..::..|:..:...:.|:.|.:...::....||
plant   486 RLMSLALGSMVQCFEWQRIGEEYVDTREEPMAMMRPATPL 525

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cyp6d2	NP_611698.1	p450	65..506	CDD:278495	99/481 (21%)
CYP81D7	NP_179900.1	p450	43..502	CDD:299894	111/535 (21%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	0	0.000