Protein Alignment Cyp6d2 and Cyp3a57

DIOPT Version :9

• Sequence 1: NP_611698.1
• Gene: Cyp6d2 / 37594
• FlyBaseID: FBgn0034756
• Length: 512
• Species: Drosophila melanogaster
• Sequence 2: NP_001093650.1
• Gene: Cyp3a57 / 622127
• MGIID: 3646373
• Length: 503
• Species: Mus musculus
• Alignment Length: 533
• Identity: 143/533 - (26%)
• Similarity: 265/533 - (49%)
• Gaps: 71/533 - (13%)

  Fly     2 WTILLTILIAGLLYRYVKRHYTH--WQRLGVDEEPAKIPFGVMDTVMKQERSLGMALADIYARHE 64
            |.:|:|    .|::.|:...|:|  :::||:   |...|..:...::.....:.....|.|.::
Mouse    12 WVLLVT----SLVFFYIYGTYSHGLFKKLGI---PGPKPLPLFGNIINYLDGMWKFDDDCYKKY- 68

  Fly    65 GKIVGIYMLNKRSILIRDAQLARQIMTSDFAS------------FHDRGVYVDEDKDPLSANLFN 117
            |||.|.|...:..:.|.|.::.:.::..:..|            |..:.:.:.||::
Mouse    69 GKIWGFYEGPQPILAIMDPEIIKIVLVKECYSVFTNRRPFGPVGFLKKSITISEDEE-------- 125

  Fly   118 LRGASWRNLRQKLTPSFSSGKIKGMFGTIDDVGDKLVQHLEGALDQSDEVEIKDVMTTYAVDIIG 182
                 |:.||..|:|:|:|.|:|.||..:...||.||::|....::.:.:.:||:...|::|:|.
Mouse   126 -----WKRLRTLLSPTFTSSKLKEMFPIMRQYGDILVRNLRREEEKEEPINMKDIFGAYSMDVIT 185

  Fly   183 SVIFGLEIDSFRNPKNEF----REISSSTSRDESLLLKIHNMSMFICP---PIAKLMNRLGYESR 240
            ....|:.|||..||::.|    ::|......|..||      |:.:.|   ||.:::|...:..:
Mouse   186 GTSCGVNIDSLNNPQDPFVQKIKKILKFKFFDPFLL------SVVLFPFLTPIYEMLNLSIFPRQ 244

  Fly   241 ILTSLRDMMKRTIEFREEHNVV-RKDMLQLLIRLRNTGKIGEDDDQVWDMETAQEQLKSMSIEKI 304
            .:...:..:|:..:.|.::|.. |.|.|||::..:|:              ..||.||::|..::
Mouse   245 SMNFFKKFVKKMKKDRLDYNQKNRVDFLQLMMNTQNS--------------KGQESLKALSDLEM 295

  Fly   305 AAQAFLFYVAGSESTAAASAFTLYELSMYPELLKEAQEEVDAVLMKHNLKPKDRFTYEAVQDLKF 369
            |||..:|...|.:.|:.:.:|.:|||:.:|::.|:.|:|:|..|..     |...||:|:.|:::
Mouse   296 AAQTLIFIFGGYDGTSTSISFIMYELATHPDVQKKLQDEIDRALPN-----KAPVTYDALMDMEY 355

  Fly   370 LDICIMETIRKYPGLPFLNRECTEDYPVPGTNHIIAKGTPILISLFGMQRDPVYFPNPNGYDPHR 434
            ||:.:.|::|.||.:..::|...:|..:.|.  .|.|||.::|.::.:.|||.|:|.|..:.|.|
Mouse   356 LDMVVNESLRLYPVVSRIDRFSKKDVEIHGV--FIPKGTIVMIPIYPLHRDPEYWPEPEDFCPER 418

  Fly   435 FDSNNM-NYDQAAYMPFGEGPRHCIALRMGKVNSKVAVAKILANFDLVQSPRKEVEFRFDAAPVL 498
            |...|. |.|...|||||.|||:||.:|...::.|:||..:|.||.:......::..:....|:.
Mouse   419 FSKENKGNIDPYIYMPFGNGPRNCIGMRFALISVKLAVTGVLQNFTVQPCEETQIPVKISRQPIF 483

  Fly   499 VTKEPLKLRLTKR 511
            ..::|:.|:...|
Mouse   484 RPEKPIILKFVSR 496

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp6d2	NP_611698.1	p450	65..506	CDD:278495	128/461 (28%)
Cyp3a57	NP_001093650.1	p450	39..493	CDD:278495	133/494 (27%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0158
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D264519at33208
OrthoFinder	1	1.000	-	-		FOG0000037
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X40
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	6	5.820