Protein Alignment Cyp6d2 and Cyp3a25

DIOPT Version :9

• Sequence 1: NP_611698.1
• Gene: Cyp6d2 / 37594
• FlyBaseID: FBgn0034756
• Length: 512
• Species: Drosophila melanogaster
• Sequence 2: NP_062766.2
• Gene: Cyp3a25 / 56388
• MGIID: 1930638
• Length: 503
• Species: Mus musculus
• Alignment Length: 532
• Identity: 145/532 - (27%)
• Similarity: 266/532 - (50%)
• Gaps: 69/532 - (12%)

  Fly     2 WTILLTILIAGLLYRYVKRHYTH--WQRLGVDEEPAKIPFGVMDTVMKQERSLGMALADIYARHE 64
            |.:|:|.|:   |: |:...|:|  :::||:   |...|..::.|:......:.....|.|.::
Mouse    12 WVLLVTSLV---LF-YIYGTYSHGLFKKLGI---PGPKPLPLLGTIFNYYDGMWKFDEDCYKKY- 68

  Fly    65 GKIVGIYMLNKRSILIRDAQLARQIMTSDFAS------------FHDRGVYVDEDKDPLSANLFN 117
            |||.|.|...:..:.|.|.::.:.::..:..|            |..:.:.:.||::
Mouse    69 GKIWGFYEGPQPILAIMDPEIIKIVLVKECYSVFTNRRFFGPVGFMKKAITISEDEE-------- 125

  Fly   118 LRGASWRNLRQKLTPSFSSGKIKGMFGTIDDVGDKLVQHLEGALDQSDEVEIKDVMTTYAVDIIG 182
                 |:.||..|:|:|:|||:|.||..:...||.||::|....::.:.:.:||:...|::|:|.
Mouse   126 -----WKRLRTLLSPTFTSGKLKEMFPIMRQYGDILVRNLRREEEKGEPISMKDIFGAYSMDVIT 185

  Fly   183 SVIFGLEIDSFRNPKNEFREISSSTSRDESLLLKIHN---MSMFICP---PIAKLMNRLGYESRI 241
            ...||:.:||..||::.|.:     ...:.|..||.:   :|:.:.|   ||.:::|...:....
Mouse   186 GTSFGVNVDSLNNPQDPFVQ-----KAKKILKFKIFDPFLLSIILFPFLTPIYEMLNFSIFPRDS 245

  Fly   242 LTSLRDMMKRTIEFREEHNVV-RKDMLQLLIRLRNTGKIGEDDDQVWDMETAQEQLKSMSIEKIA 305
            :...:..:||..:.|...|.. |.|.|||::..:|:              ..||..|::|..::|
Mouse   246 MNFFKKFVKRMKKERLASNQKNRVDFLQLMMNTQNS--------------KGQESQKALSDLEMA 296

  Fly   306 AQAFLFYVAGSESTAAASAFTLYELSMYPELLKEAQEEVDAVLMKHNLKPKDRFTYEAVQDLKFL 370
            |||.:|...|.::|:.:.:..:|||:.:|::.|:.|:|:|     ..|..|...||:|:.|:::|
Mouse   297 AQAVIFIFGGYDATSTSISLIMYELATHPDVQKKLQDEID-----RTLPNKAPVTYDALMDMEYL 356

  Fly   371 DICIMETIRKYPGLPFLNRECTEDYPVPGTNHIIAKGTPILISLFGMQRDPVYFPNPNGYDPHRF 435
            |:.:.|::|.||....|.|...:|..:.|.  .|.|||.::|.::.:.|:|.|:|.|..:.|.||
Mouse   357 DMVVNESLRLYPIAIRLERVSKKDVEINGV--FIPKGTVVMIPIYPLHRNPEYWPEPQEFCPERF 419

  Fly   436 DSNNM-NYDQAAYMPFGEGPRHCIALRMGKVNSKVAVAKILANFDLVQSPRKEVEFRFDAAPVLV 499
            ...|. |.|...|||||.|||:||.:|...::.|:||..:|.||.:......::..:....|:..
Mouse   420 SKENKGNIDPYIYMPFGNGPRNCIGMRFALISIKLAVIGVLQNFTVQPCEETQIPLKISREPIFQ 484

  Fly   500 TKEPLKLRLTKR 511
            .::|:.|::..|
Mouse   485 PEKPIILKVVSR 496

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp6d2	NP_611698.1	p450	65..506	CDD:278495	128/460 (28%)
Cyp3a25	NP_062766.2	p450	39..493	CDD:278495	134/493 (27%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0158
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D264519at33208
OrthoFinder	1	1.000	-	-		FOG0000037
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X40
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	6	5.820