Protein Alignment Cyp6d2 and cyp3a65

DIOPT Version :10

• Sequence 1: NP_611698.1
• Gene: Cyp6d2 / 37594
• FlyBaseID: FBgn0034756
• Length: 512
• Species: Drosophila melanogaster
• Sequence 2: NP_001032515.2
• Gene: cyp3a65 / 553969
• ZFINID: ZDB-GENE-050604-1
• Length: 517
• Species: Danio rerio
• Alignment Length: 538
• Identity: 148/538 - (27%)
• Similarity: 257/538 - (47%)
• Gaps: 69/538 - (12%)

  Fly     2 WTILLTILIAGLLYRYVKRHYTHWQRLGVDEEPAKIPFGVMDTVMKQERSLGMALADIYARHEGK 66
            || ||..|:| ||..|....:.::::||: ..|..|||  ..|:::.:....:...|.:.:: |:
Zfish     8 WT-LLAFLVA-LLVIYGSWPHRYFKKLGI-PGPKTIPF--FGTMLRYKDGFHVFDMDCFEKY-GR 66

  Fly    67 IVGIYMLNKRSILIRDAQLARQIMTSD-FASFHDR-----------GVYVDEDKDPLSANLFNLR 119
            |.|||...:..:.|.|..:.:.::..: ::.|.:|           .|.:.||.|
Zfish    67 IWGIYDGRQPVLCIMDQTIIKTVLIKECYSLFTNRRNFRLNGALYDAVSIAEDDD---------- 121

  Fly   120 GASWRNLRQKLTPSFSSGKIKGMFGTIDDVGDKLVQHLEGALDQSDEVEIKDVMTTYAVDIIGSV 184
               ||.:|..|:|||:||::|.|||.:......||..:.....:.:..:||:....|::|::.|.
Zfish   122 ---WRRIRSVLSPSFTSGRLKEMFGIMKKHSHILVDSMGKTAKRGESADIKEFFGAYSMDVVTST 183

  Fly   185 IFGLEIDSFRNPKNEFREISSSTSRDESLLLKIHNMSMFIC----PPIAKLMNRLGYESRILTSL 245
            .|.::|||..|||:.|     .|:..:.|...:.| .:|:.    |.:|.::.::.: :...||:
Zfish   184 AFSVDIDSLNNPKDPF-----VTNIKKMLKFDLLN-PLFLLIAFFPFMAPVLEKMDF-ALFPTSV 241

  Fly   246 RDMM----------KRTIEFREEHNVVRKDMLQLLIRLRNTGKIGEDDDQVWDMETAQEQLKSMS 300
            .|..          :.|....:::...|.|.|||::. ..||...:.|        .:...|.:|
Zfish   242 TDFFYAALQKIKSDRDTKTVAKDNTKKRVDFLQLMVD-SQTGVKHKSD--------GEHTEKGLS 297

  Fly   301 IEKIAAQAFLFYVAGSESTAAASAFTLYELSMYPELLKEAQEEVDAVLMKHNLKPKDRFTYEAVQ 365
            ..:|.:|:.:|..||.|::::..:|..|.|:..||.:|:.|||:|...  .|..|.|   ||.:.
Zfish   298 DHEILSQSMIFIFAGYETSSSTLSFLFYNLATNPETMKKLQEEIDETF--PNQAPVD---YETLM 357

  Fly   366 DLKFLDICIMETIRKYPGLPFLNRECTEDYPVPGTNHIIAKGTPILISLFGMQRDPVYFPNPNGY 430
            .:.:||..:.|::|.||....|.|.|.:...:.|.  :|.|...:::..:.:.|||.|:..|..:
Zfish   358 SMDYLDAALSESLRLYPVAARLERVCKKTVEINGL--LIPKDLVVMVPTYALHRDPDYWSEPESF 420

  Fly   431 DPHRFDSNNM-NYDQAAYMPFGEGPRHCIALRMGKVNSKVAVAKILANFDLVQSPRKEVEFRFDA 494
            .|.||...|. :.|...|||||.|||:||.:|..:|..|:|:.:||..||:......:|......
Zfish   421 KPERFTKGNKESIDPYMYMPFGLGPRNCIGMRFAQVTMKLAIVEILQRFDVSVCDETQVPLELGF 485

  Fly   495 APVLVTKEPLKLRLTKRK 512
            ..:|..|:|:||:|..||
Zfish   486 NGLLSPKDPIKLKLQPRK 503

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp6d2	NP_611698.1	CYP6-like	63..505	CDD:410679	126/468 (27%)
cyp3a65	NP_001032515.2	cytochrome_P450	63..498	CDD:477761	127/471 (27%)