Protein Alignment Cyp6d2 and Cyp3a73

DIOPT Version :10

• Sequence 1: NP_611698.1
• Gene: Cyp6d2 / 37594
• FlyBaseID: FBgn0034756
• Length: 512
• Species: Drosophila melanogaster
• Sequence 2: XP_038945885.1
• Gene: Cyp3a73 / 498198
• RGDID: 1595705
• Length: 504
• Species: Rattus norvegicus
• Alignment Length: 528
• Identity: 151/528 - (28%)
• Similarity: 265/528 - (50%)
• Gaps: 60/528 - (11%)

  Fly     2 WTILLTILIAGLLYRYVKRHYTHWQRLGVDEEPAKIPFGVMDTVMKQERSLGMALADIYARHEGK 66
            |.:|..||:  |.||:..|.:..:::.|: ..|..:||  :.||:...|.|.....:.|.:. ||
  Rat    12 WLLLAIILV--LFYRFGTRTHGIFKKQGI-PGPKPLPF--LGTVLNYYRGLWKFDMECYKKC-GK 70

  Fly    67 IVGIYMLNKRSILIRDAQLARQIMTSD-FASFHDR------GVYVDEDKDPLSANLFNLRGASWR 124
            |.|::........|.|.::.:.::..: |:.|.:|      |:        :|.::...:...|:
  Rat    71 IWGLFDGQTPVFAIMDTEMIKSVLVKECFSVFTNRRNIGPVGI--------MSKSISVAKDEEWK 127

  Fly   125 NLRQKLTPSFSSGKIKGMFGTIDDVGDKLVQHLEGALDQSDEVEIKDVMTTYAVDIIGSVIFGLE 189
            ..|..|:|:|:||::|.||..|:..||.||::|:..:::...:.:|:|...|::|:|.|..|.:.
  Rat   128 RYRAFLSPTFTSGRLKEMFPIIEHYGDILVKYLKQKVEKGKPLAMKEVFGAYSMDVITSTSFEVN 192

  Fly   190 IDSFRNPKNEFREISSSTSR---DESLLLKIHNMSMFICP---PIAKLMNRLGYESRILTSLRDM 248
            |:|..|||:.|.|......|   .:.|.|     |:.:.|   ||.:::|...:....:...:..
  Rat   193 INSINNPKDPFVEKVKKFQRFDFFDPLFL-----SVVLFPFLTPIYEMLNICLFPKDSVAFFQKF 252

  Fly   249 ---MKRT-IEFREEHNVVRKDMLQLLIRLRNTGKIGEDDDQVWDMETAQEQLKSMSIEKIAAQAF 309
               ||:| ::.:.:|.|   |.|||::...|..|     |:|        ..|::|..:|.|||.
  Rat   253 VYRMKQTRLDSKHKHRV---DFLQLMMNAHNNSK-----DKV--------SHKALSDIEIVAQAI 301

  Fly   310 LFYVAGSESTAAASAFTLYELSMYPELLKEAQEEVDAVLMKHNLKPKDRFTYEAVQDLKFLDICI 374
            :|..|..|:|::..:|.||.|:.:|:..|:.|||:|..|  .|..|.   ||:.|.::::||:.:
  Rat   302 IFIFASYETTSSTLSFVLYSLATHPDSQKKLQEEIDRAL--PNKAPP---TYDTVMEMEYLDMVL 361

  Fly   375 METIRKYPGLPFLNRECTEDYPVPGTNHIIAKGTPILISLFGMQRDPVYFPNPNGYDPHRFDSNN 439
            .||.|.||....|.|.|.:|..:.|.  .|.||:.::|..:.:|.||.::|.|..:.|.||...|
  Rat   362 NETPRLYPIGYRLERVCKKDIKLDGV--FIPKGSVVMIPFYTLQHDPQHWPEPEEFLPERFSKEN 424

  Fly   440 M-NYDQAAYMPFGEGPRHCIALRMGKVNSKVAVAKILANFDLVQSPRKEVEFRFDAAPVLVTKEP 503
            . :.|...|:|||.|||:||.:|...:|.|:|:.|:|.||........::..:.....:...::|
  Rat   425 KGSIDPYVYLPFGNGPRNCIGMRFALMNMKLALTKVLQNFSFQLCEETQIPLKLSRQRLFGPEKP 489

  Fly   504 LKLRLTKR 511
            :.|::..|
  Rat   490 IVLKVVPR 497

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp6d2	NP_611698.1	CYP6-like	63..505	CDD:410679	132/459 (29%)
Cyp3a73	XP_038945885.1	CYP3A	67..493	CDD:410743	132/462 (29%)