Protein Alignment Cyp6d2 and Cyp3a44

DIOPT Version :9

• Sequence 1: NP_611698.1
• Gene: Cyp6d2 / 37594
• FlyBaseID: FBgn0034756
• Length: 512
• Species: Drosophila melanogaster
• Sequence 2: NP_796354.1
• Gene: Cyp3a44 / 337924
• MGIID: 2449818
• Length: 504
• Species: Mus musculus
• Alignment Length: 524
• Identity: 145/524 - (27%)
• Similarity: 263/524 - (50%)
• Gaps: 52/524 - (9%)

  Fly     3 TILLTILIAGLLYRYVKRHYTHWQRLGVDEEPAKIPFGVMDTVMKQERSLGMALADIYARHEGKI 67
            |::|..:|..|||||..|.:..:::.|: ..|..:||  :.||:.....:.....:.|.:: ||.
Mouse    11 TLVLLAIILVLLYRYGTRTHGLFKKQGI-PGPKPLPF--LGTVLNYYTGIWKFDMECYEKY-GKT 71

  Fly    68 VGIYMLNKRSILIRDAQLARQIMTSDFAS-FHDR-----------GVYVDEDKDPLSANLFNLRG 120
            .|::......::|.|.:..:.::..|..| |.:|           .:.:.:|::
Mouse    72 WGLFDGQTPLLVITDPETIKNVLVKDCLSVFTNRREFGPVGIMSKAISISKDEE----------- 125

  Fly   121 ASWRNLRQKLTPSFSSGKIKGMFGTIDDVGDKLVQHLEGALDQSDEVEIKDVMTTYAVDIIGSVI 185
              |:..|..|:|:|:||::|.||..|:..||.||::|....::...|.:|||:..|::|:|.|..
Mouse   126 --WKRYRALLSPTFTSGRLKEMFPVIEQYGDILVKYLRQEAEKGMPVAMKDVLGAYSMDVITSTS 188

  Fly   186 FGLEIDSFRNPKNEFREISSSTSRDESLLLKIHNMSMF-ICPPIAKLMNRLGYESRILTSLRDMM 249
            ||:.:||..||::.|.|.:....|.:.....:.::.:| :..|:.:::|...:.:..:...:..:
Mouse   189 FGVNVDSLNNPEDPFVEEAKKFLRVDFFDPLLFSVVLFPLLTPVYEMLNICMFPNDSIEFFKKFV 253

  Fly   250 KRTIEFREEHNVV-RKDMLQLLIRLRNTGKIGEDDDQVWDMETAQEQLKSMSIEKIAAQAFLFYV 313
            .|..|.|.:.|.. |.|.|||::...|..|   |.|          ..|:.|..:|..|:.:|..
Mouse   254 DRMQESRLDSNQKHRVDFLQLMMNSHNNSK---DKD----------SHKAFSNMEITVQSIIFIS 305

  Fly   314 AGSESTAAASAFTLYELSMYPELLKEAQEEVDAVLMKHNLKPKDRFTYEAVQDLKFLDICIMETI 378
            ||.|:|::..:||||.|:.:|::.|:.|.|:|..|..     |...|.:.|.::::||:.:.||:
Mouse   306 AGYETTSSTLSFTLYCLATHPDIQKKLQAEIDKALPN-----KATPTCDTVMEMEYLDMVLNETL 365

  Fly   379 RKYPGLPFLNRECTEDYPVPGTNHIIAKGTPILISLFGMQRDPVYFPNPNGYDPHRFDSNNM-NY 442
            |.||.:..|.|.|.:|..:.|.  .|.||:.::|..:.:..||.::|:|..:.|.||...|. :.
Mouse   366 RLYPIVTRLERVCKKDVELNGV--YIPKGSMVMIPSYALHHDPQHWPDPEEFQPERFSKENKGSI 428

  Fly   443 DQAAYMPFGEGPRHCIALRMGKVNSKVAVAKILANFDLVQSPRKEVEFRFDAAPVLVTKEPLKLR 507
            |...|:|||.|||:||.:|...:|.|:||.|:|.||........::..:.....:|..::|:.|:
Mouse   429 DPYVYLPFGIGPRNCIGMRFALMNMKLAVTKVLQNFSFQPCQETQIPLKLSRQGILQPEKPIVLK 493

  Fly   508 LTKR 511
            :..|
Mouse   494 VVPR 497

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp6d2	NP_611698.1	p450	65..506	CDD:278495	127/455 (28%)
Cyp3a44	NP_796354.1	p450	39..494	CDD:278495	134/490 (27%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0158
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D264519at33208
OrthoFinder	1	1.000	-	-		FOG0000037
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X40
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	7	6.820