Protein Alignment Cyp6d2 and Cyp3a18

DIOPT Version :10

• Sequence 1: NP_611698.1
• Gene: Cyp6d2 / 37594
• FlyBaseID: FBgn0034756
• Length: 512
• Species: Drosophila melanogaster
• Sequence 2: NP_665725.2
• Gene: Cyp3a18 / 252931
• RGDID: 628709
• Length: 497
• Species: Rattus norvegicus
• Alignment Length: 533
• Identity: 141/533 - (26%)
• Similarity: 260/533 - (48%)
• Gaps: 71/533 - (13%)

  Fly     2 WTILLTILIAGLLYRYVKRHYTH--WQRLGVDEEPAKIPFGVMDTVMKQERSLGMALADIYARHE 64
            |.:|.|    .|:..|:...|:|  :::||:   |...|..:..|:......:.....|.|.::
  Rat    12 WVLLAT----SLMLFYIYGTYSHGLFKKLGI---PGPKPVPLFGTIFNYGDGMWKFDDDCYKKY- 68

  Fly    65 GKIVGIYMLNKRSILIRDAQLARQIMTSDFAS------------FHDRGVYVDEDKDPLSANLFN 117
            |||.|.|...:..:.|.|.::.:.::..:..|            |..:.:.:.||::
  Rat    69 GKIWGFYEGPQPFLAIMDPEIIKMVLVKECYSVFTNRRCFGPMGFMKKAITMSEDEE-------- 125

  Fly   118 LRGASWRNLRQKLTPSFSSGKIKGMFGTIDDVGDKLVQHLEGALDQSDEVEIKDVMTTYAVDIIG 182
                 |:.||..|:|:|:|||:|.||..:...||.|:::|.....:.:.:.:||:...|::|:|.
  Rat   126 -----WKRLRTILSPTFTSGKLKEMFPLMRQYGDTLLKNLRREEAKGEPINMKDIFGAYSMDVIT 185

  Fly   183 SVIFGLEIDSFRNPKNEF----REISSSTSRDESLLLKIHNMSMFICP---PIAKLMNRLGYESR 240
            ...||:.:||..||::.|    ::|......|..||      |:.:.|   ||.:::|...:..:
  Rat   186 GTSFGVNVDSLNNPQDPFVQKAKKILKFQIFDPFLL------SVVLFPFLTPIYEMLNFSIFPRQ 244

  Fly   241 ILTSLRDMMKRTIEFREEHN-VVRKDMLQLLIRLRNTGKIGEDDDQVWDMETAQEQLKSMSIEKI 304
            .:...:..:|...:.|.:.| ..|.|.|||::..:|:              ..||..|::|..::
  Rat   245 SMNFFKKFVKTMKKNRLDSNQKSRVDFLQLMMNTQNS--------------KGQESQKALSDLEM 295

  Fly   305 AAQAFLFYVAGSESTAAASAFTLYELSMYPELLKEAQEEVDAVLMKHNLKPKDRFTYEAVQDLKF 369
            ||||.:|...|.::|:.:.:|.:|||:..|.:.|:.|.|:|..|..     |...||:|:.::::
  Rat   296 AAQAIIFIFGGYDATSTSISFIMYELATRPNVQKKLQNEIDRALPN-----KAPVTYDALMEMEY 355

  Fly   370 LDICIMETIRKYPGLPFLNRECTEDYPVPGTNHIIAKGTPILISLFGMQRDPVYFPNPNGYDPHR 434
            ||:.:.|::|.||....|:|...:|..:.|.  .|.|||.:.|.::.:.|:|.|:..|..::|.|
  Rat   356 LDMVVNESLRLYPIATRLDRVSKKDVEINGV--FIPKGTVVTIPIYPLHRNPEYWLEPEEFNPER 418

  Fly   435 FDSNNM-NYDQAAYMPFGEGPRHCIALRMGKVNSKVAVAKILANFDLVQSPRKEVEFRFDAAPVL 498
            |...|. :.|...|:|||.|||:||.:|...::.|:||..:|.||::....:.::..:....|:.
  Rat   419 FSKENKGSIDPYVYLPFGNGPRNCIGMRFALISMKLAVIGVLQNFNIQPCEKTQIPLKISRQPIF 483

  Fly   499 VTKEPLKLRLTKR 511
            ..:.|:.|:|..|
  Rat   484 QPEGPIILKLVSR 496

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp6d2	NP_611698.1	CYP6-like	63..505	CDD:410679	124/462 (27%)
Cyp3a18	NP_665725.2	CYP3A	67..492	CDD:410743	124/465 (27%)