Protein Alignment Cyp6d2 and cyp-13A7

DIOPT Version :10

• Sequence 1: NP_611698.1
• Gene: Cyp6d2 / 37594
• FlyBaseID: FBgn0034756
• Length: 512
• Species: Drosophila melanogaster
• Sequence 2: NP_496114.1
• Gene: cyp-13A7 / 188362
• WormBaseID: WBGene00000372
• Length: 518
• Species: Caenorhabditis elegans
• Alignment Length: 535
• Identity: 135/535 - (25%)
• Similarity: 254/535 - (47%)
• Gaps: 68/535 - (12%)

  Fly     2 WTILLTILIAGLLYRYVKRHYTHWQRLGVDEEPAKIPF-GVMDTVMKQERSLGMALADIYARHEG 65
            ::||:.|.|...:..|....::.|.|.|| :.|..:|| ||:......|....:..:: :.:..|
 Worm     3 FSILIAIAIFVGIISYYLWIWSFWIRKGV-KGPRGLPFLGVIHKFTNYENPGALKFSE-WTKKYG 65

  Fly    66 KIVGIYMLNKRSILIRDAQLARQIMTSDFASFHDR---GVYVDEDKD---PLSANLFNLRGASWR 124
            .:.||....:::::|.|.:...::....|.:|:.|   .:..|.:|:   ||.|    .:|..|:
 Worm    66 PVYGITEGVEKTLVISDPEFVHEVFVKQFDNFYGRKLTAIQGDPNKNKRVPLVA----AQGHRWK 126

  Fly   125 NLRQKLTPSFSSGKIKGMFGTIDDVGDKLVQHLEGALDQSDEVEIKDVMTTYAVDIIGSVIFGLE 189
            .||...:|:||:..::.:.||:::...:||:.||.|..:...:::.:....:.:||||.:..|.|
 Worm   127 RLRTLASPTFSNKSLRKIMGTVEESVTELVRSLEKASAEGKTLDMLEYYQEFTMDIIGKMAMGQE 191

  Fly   190 ID-SFRNP-----KNEFREISSSTSRDESLLLKIHNMSMFICPPIAKLMNR---LGYESRILTSL 245
            .. .||||     |..|:|       ..:.:..|..:..|:...:..:..:   |...:.|.:.|
 Worm   192 KSLMFRNPMLDKVKTIFKE-------GRNNVFMISGIFPFVGIALRNIFAKFPSLQMATDIQSIL 249

  Fly   246 RDMMKRTIEFRE-------EHNVVRKDMLQLLIRLRNTGKIGEDDDQVWDMETAQEQL----KSM 299
            ...:.:.:|.||       |.:...:|.:.|.:..|:|....|.:.   :.:.|:.::    |.:
 Worm   250 EKALNKRLEQREADEKAGIEPSGEPQDFIDLFLDARSTVDFFEGEA---EQDFAKSEVLKVDKHL 311

  Fly   300 SIEKIAAQAFLFYVAGSESTAAASAFTLYELSMYPELLKEAQEEVDAVLMKHNLKPKDRFTYEAV 364
            :.::|..|.|:|.:||.::||.:.:::.|.|:.:||:.|:.|||||...      |....|::.:
 Worm   312 TFDEIIGQLFVFLLAGYDTTALSLSYSSYLLATHPEIQKKLQEEVDREC------PDPEVTFDQL 370

  Fly   365 QDLKFLDICIMETIRKYPGLPFL-NRECTEDYPVPGTNHIIAKGTPILISLFGMQRDP-VYFPNP 427
            ..||:|:..:.|.:|.||....: ||:|.:...|.|..  |..||.|.:..:.:..|| |:..:.
 Worm   371 SKLKYLECVVKEALRLYPLASLVHNRKCLKTTNVLGME--IEAGTNINVDTWSLHHDPKVWGDDV 433

  Fly   428 NGYDPHRFDS-NNMNYDQAAYMPFGEGPRHCIALRMGKVNSKVAVAKILANFDLVQSPRKEVEFR 491
            |.:.|.|::| :.:.:.:..|:|||.|||.||.:|:..:..|:.:..||.|            :.
 Worm   434 NEFKPERWESGDELFFAKGGYLPFGMGPRICIGMRLAMMEMKMLLTNILKN------------YT 486

  Fly   492 FDAAPVLVTKEPLKL 506
            |:..|..|.  ||||
 Worm   487 FETTPETVI--PLKL 499

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp6d2	NP_611698.1	CYP6-like	63..505	CDD:410679	117/470 (25%)
cyp-13A7	NP_496114.1	CYP3A-like	63..507	CDD:410678	120/473 (25%)