Protein Alignment Cyp6d2 and cyp-13A3

DIOPT Version :10

• Sequence 1: NP_611698.1
• Gene: Cyp6d2 / 37594
• FlyBaseID: FBgn0034756
• Length: 512
• Species: Drosophila melanogaster
• Sequence 2: NP_496110.1
• Gene: cyp-13A3 / 188359
• WormBaseID: WBGene00011675
• Length: 520
• Species: Caenorhabditis elegans
• Alignment Length: 542
• Identity: 141/542 - (26%)
• Similarity: 256/542 - (47%)
• Gaps: 86/542 - (15%)

  Fly     6 LTILIAGLLYRYVKRHY----THWQRLGVDEEPAKIP-FGVMDTVMKQERSLGMALADIYARHEG 65
            |:||||..|:..|..:|    :.|.|.|: :.|..:| ||:::.....|:...:.|.| :.:..|
 Worm     3 LSILIAIALFIGVFTYYLWIWSFWMRKGI-KGPRGLPFFGIINAFQSYEKPWILRLGD-WTKEYG 65

  Fly    66 KIVGIYMLNKRSILIRDAQLARQIMTSDFASFHDR---GVYVDEDKDPLSANLFNLRGASWRNLR 127
            .:.|.....::::::.|.:...::....|.:|:.|   .:..|.|||| ..:|...:|..|:.||
 Worm    66 PMYGFTDGVEKTLVVSDPEFVHEVFVKQFDNFYARKQNPLQGDPDKDP-RIHLVTSQGHRWKRLR 129

  Fly   128 QKLTPSFSSGKIKGMFGTIDDVGDKLVQHLEGALDQSDEVEIKDVMTTYAVDIIGSVIFGLEID- 191
            ...:|:||:..::.:|.|:::...::::|||........::|.:....:.:||||.:..|....
 Worm   130 TLASPTFSNKSLRKIFSTVEESVAEMMRHLEKGTAGGKTIDILEYYQEFTMDIIGKIAMGQSGSM 194

  Fly   192 SFRNP-KNEFREISSSTSRDESLLLKIHNMSMFIC--PPIAKLMNRLGYE----SRILTSLRDMM 249
            .|.|| .::.|.|.::..          |:...||  .|....:.|..:.    ::.:|||...:
 Worm   195 MFENPWLDKIRAIFNTRG----------NIIFIICGIVPFTGSIFRWFFSKVPTAQTVTSLMHTL 249

  Fly   250 KRTIEFREEHNVV-----------RKDMLQLLIRLRNTGKIGEDDDQVWDMET----AQEQL--- 296
            :..:..|.|....           .:|.:.|.:      .:..|.|.:.| ||    |:.|:
 Worm   250 EIALTKRVEQRAADEKAGIESSGEPQDFIDLFL------DVQADTDFLED-ETKNGFARSQIVKV 307

  Fly   297 -KSMSIEKIAAQAFLFYVAGSESTAAASAFTLYELSMYPELLKEAQEEVDAVLMKHNLKPKDRFT 360
             |.::.::|..|.|:|.:||.::||.:.:::.|.|:.:||:.|:.|||||...      |....|
 Worm   308 DKHLTFDEIIGQLFVFLLAGYDTTALSLSYSSYLLARHPEIQKKLQEEVDREC------PDPEVT 366

  Fly   361 YEAVQDLKFLDICIMETIRKYPGLPFL-NRECTEDYPVPGTNHIIAKGTPILISLFGMQRDPVYF 424
            ::.:..||:::..|.||:|.||....: ||:|.:...|.|..  |.:||.:....:.:..||.::
 Worm   367 FDQLSKLKYMECVIKETLRLYPLASIVHNRKCMKSTTVLGMK--IEEGTNVQADTWTLHYDPKFW 429

  Fly   425 -PNPNGYDPHRFDSNNMNYDQA----AYMPFGEGPRHCIALRMGKVNSKVAVAKILANFDLVQSP 484
             .|.|.:.|.|::|.:   :||    ||:|||.|||.||.:|:..:..|:.:|:||..:.|
 Worm   430 GENANEFKPERWESGD---EQAVAKGAYLPFGLGPRICIGMRLAYMEEKMLLAQILKKYSL---- 487

  Fly   485 RKEVEFRFDAAPVLVTKEPLKL 506
                |..|:      |..||||
 Worm   488 ----ETTFE------THIPLKL 499

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp6d2	NP_611698.1	CYP6-like	63..505	CDD:410679	120/477 (25%)
cyp-13A3	NP_496110.1	CYP3A-like	63..509	CDD:410678	123/480 (26%)