Protein Alignment Cyp6d2 and cyp-13A5

DIOPT Version :10

• Sequence 1: NP_611698.1
• Gene: Cyp6d2 / 37594
• FlyBaseID: FBgn0034756
• Length: 512
• Species: Drosophila melanogaster
• Sequence 2: NP_496112.1
• Gene: cyp-13A5 / 188356
• WormBaseID: WBGene00011672
• Length: 520
• Species: Caenorhabditis elegans
• Alignment Length: 539
• Identity: 136/539 - (25%)
• Similarity: 261/539 - (48%)
• Gaps: 57/539 - (10%)

  Fly     6 LTILIAGLLYRYVKRHY----THWQRLGVDEEPAKIP-FGVMDTVMKQERSLGMALADIYARHEG 65
            |:|||||..:..:..:|    :.|.|.|| :.|...| |||:......|.. |:.....:.:..|
 Worm     3 LSILIAGASFIGLLTYYIWIWSFWIRKGV-KGPRGFPFFGVIHEFQDYENP-GLLKLGEWTKEYG 65

  Fly    66 KIVGIYMLNKRSILIRDAQLARQIMTSDFASFHDR---GVYVDEDKDPLSANLFNLRGASWRNLR 127
            .|.||....::::::.:.:...::....|.:|:.|   .:..|.:|:. .|:|.:.:|..|:.||
 Worm    66 PIYGITEGVEKTLIVSNPEFVHEVFVKQFDNFYGRKTNPIQGDPNKNK-RAHLVSAQGHRWKRLR 129

  Fly   128 QKLTPSFSSGKIKGMFGTIDDVGDKLVQHLEGALDQSDEVEIKDVMTTYAVDIIGSVIFG-LEID 191
            ...:|:||:..::.:..|:::...:|::||:.|..:...|::.|....:.:||||.:..| .|..
 Worm   130 TLSSPTFSNKNLRKIMSTVEETVVELMRHLDDASAKGKAVDLLDYYQEFTLDIIGRIAMGQTESL 194

  Fly   192 SFRNP-----KNEFREISSSTSRDESLLLKIHNMSMFICPPIAKLMNR---LGYES-----RILT 243
            .||||     |..|::     .|....|:.    .:|   |||..|.|   :.:.|     .|::
 Worm   195 MFRNPMLPKVKGIFKD-----GRKLPFLVS----GIF---PIAGTMFREFFMRFPSIQPAFDIMS 247

  Fly   244 SLRDMMKRTIEFRE-------EHNVVRKDMLQLLIRLRNTGKIGEDDDQVWDMETAQEQL-KSMS 300
            ::...:.:.:|.|.       |.:...:|.:.|.:..|......|::..:...:|...:: |.::
 Worm   248 TVEKALNKRLEQRAADEKAGIEPSGEPQDFIDLFLDARANVDFFEEESALGFAKTEIAKVDKQLT 312

  Fly   301 IEKIAAQAFLFYVAGSESTAAASAFTLYELSMYPELLKEAQEEVDAVLMKHNLKPKDRFTYEAVQ 365
            .::|..|.|:|.:||.::||.:.:::.|.|:.:||:.|:.|||||...      |....|::.:.
 Worm   313 FDEIIGQLFVFLLAGYDTTALSLSYSSYLLARHPEIQKKLQEEVDREC------PNPEVTFDQIS 371

  Fly   366 DLKFLDICIMETIRKYPGLPFL-NRECTEDYPVPGTNHIIAKGTPILISLFGMQRDP-VYFPNPN 428
            .||:::..:.|.:|.||....: ||:|.::..|.|..  |.|||.:.:..:.:..|| |:..:.|
 Worm   372 KLKYMECVVKEALRMYPLASIVHNRKCMKETNVLGVQ--IEKGTNVQVDTWTLHYDPKVWGEDAN 434

  Fly   429 GYDPHRFDS-NNMNYDQAAYMPFGEGPRHCIALRMGKVNSKVAVAKILANFDLVQSPRKEVEFRF 492
            .:.|.|::| :.:.|.:..|:|||.|||.||.:|:..:..|:.:..||..:....|.:.|:..:.
 Worm   435 EFRPERWESGDELFYAKGGYLPFGMGPRICIGMRLAMMEKKMLLTHILKKYTFETSTQTEIPLKL 499

  Fly   493 DAAPVLVTKEPLKLRLTKR 511
            ..:.....:. :.|:||.|
 Worm   500 VGSATTAPRS-VMLKLTPR 517

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp6d2	NP_611698.1	CYP6-like	63..505	CDD:410679	114/469 (24%)
cyp-13A5	NP_496112.1	CYP3A-like	63..511	CDD:410678	114/469 (24%)