Protein Alignment Cyp6d2 and cyp-25A1

DIOPT Version :10

• Sequence 1: NP_611698.1
• Gene: Cyp6d2 / 37594
• FlyBaseID: FBgn0034756
• Length: 512
• Species: Drosophila melanogaster
• Sequence 2: NP_497775.3
• Gene: cyp-25A1 / 183247
• WormBaseID: WBGene00007963
• Length: 502
• Species: Caenorhabditis elegans
• Alignment Length: 542
• Identity: 128/542 - (23%)
• Similarity: 246/542 - (45%)
• Gaps: 72/542 - (13%)

  Fly     1 MWTILLTILIAGLLYRYV------KRHYTHWQRLGVD-EEPAKIPFGVMDTVMKQERSLGMALAD 58
            |..::|:.|:..:...::      :..:...:::|:. .||......:..|..::|: ||...|:
 Worm     1 MALLILSSLVISIFTFFIYIILARRERFKLREKIGLSGPEPHWFLGNLKQTAERKEK-LGYDDAN 64

  Fly    59 IYAR--HE--GKIVGIYMLNKRSILIRDAQLARQIMTSDFASFHDRGVYVDEDKDPLSAN-LFNL 118
            .:..  ||  |:..|||..::.:|:|.:.:..:::...:|::|.||.|....:.:.|:|: |.|.
 Worm    65 RWFNELHEQYGETFGIYYGSQMNIVISNEKDIKEVFIKNFSNFSDRSVPSIYEANQLTASLLMNS 129

  Fly   119 RGASWRNLRQKLTPSFSSGKIKGMFGTIDDVGDKLVQHLEGALDQSDEVEIKDVMTTYAVDIIGS 183
            ..:.|::.|..:.|.||:||:|.|..||:...|..:..|........:.:|.|......:|:||.
 Worm   130 YSSGWKHTRSAIAPIFSTGKMKAMQETINSKVDLFLDILREKASSGQKWDIYDDFQGLTLDVIGK 194

  Fly   184 VIFGLEIDSFRNPKNEF-----REISSSTSRDESLL--------LKIHNMSMFICPPIAKLMNRL 235
            ..|.::.:..|:..:.|     :.||:...|...::        |.....:::...|:|..
 Worm   195 CAFAIDSNCQRDRNDVFYVNAKKYISNIDIRHSKIIAASVLLPELSTFWKALYKYTPLADA---- 255

  Fly   236 GYESRILTSLRDMMKRTIEFREEHNVVRKDMLQLLIRLRNTGKIGEDDDQVWDMETAQEQLKSMS 300
              |..::..|.::.:|........:|   |:|:||:.       .|||           :.|.|:
 Worm   256 --EIPLVEGLSNVYERRRGGEGSDSV---DLLKLLLN-------REDD-----------KSKPMT 297

  Fly   301 IEKIAAQAFLFYVAGSESTAAASAFTLYELSMYPELLKEAQEEVDAVLMKHNLKPKDRFTYEAVQ 365
            .:::....|.|.:||.|:|:.|..:..|.||.||.:.::..||:      ...|.....||:::.
 Worm   298 KQEVIENCFAFLLAGYETTSTAMTYCSYLLSKYPNVQQKLYEEI------MEAKENGGLTYDSIH 356

  Fly   366 DLKFLDICIMETIRKYPG-LPFLNRECTEDYPVPGTNHIIAKGTPILISLFGMQRDPVYFPNPNG 429
            ::|:||....||:|.||. :.|:.|.|.||..:.|  ....||..::.....:.|:|..:.:|..
 Worm   357 NMKYLDCVYKETLRFYPPVIHFIRRLCREDITIRG--QFYPKGAIVVCLPHTVHRNPENWDSPEE 419

  Fly   430 YDPHRFDSNNMNYDQAAYMPFGEGPRHCIALRMGKVNSKVAVAKILANFDLVQSPRKEVEFRFDA 494
            :.|.||::.........::|||.|||:|:.:|..::..|..:.|:|..|:|     |:.|...|.
 Worm   420 FHPERFENWEEKSSSLKWIPFGVGPRYCVGMRFAEMEFKTTIVKLLDTFEL-----KQFEGEADL 479

  Fly   495 AP-----VLVTKEPLKLRLTKR 511
            .|     ::...:|::|.|..|
 Worm   480 IPDCNGVIMRPNDPVRLHLKPR 501

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp6d2	NP_611698.1	CYP6-like	63..505	CDD:410679	114/463 (25%)
cyp-25A1	NP_497775.3	CYP3A-like	73..495	CDD:410678	112/461 (24%)