Protein Alignment Cyp6d2 and Cyp3a62

DIOPT Version :9

• Sequence 1: NP_611698.1
• Gene: Cyp6d2 / 37594
• FlyBaseID: FBgn0034756
• Length: 512
• Species: Drosophila melanogaster
• Sequence 2: NP_001019403.1
• Gene: Cyp3a62 / 170509
• RGDID: 1595919
• Length: 497
• Species: Rattus norvegicus
• Alignment Length: 542
• Identity: 147/542 - (27%)
• Similarity: 265/542 - (48%)
• Gaps: 89/542 - (16%)

  Fly     2 WTILLTILIAGLLYRYVKRHYTHWQRLGVDEEPAKIPFGVMDTVMKQERSLGMALADIYA----- 61
            |.:|.|||:  |||.|....:.::::||: ..|..:||            :|..||..:.
  Rat    12 WMLLATILV--LLYLYGTSTHGNFKKLGI-SGPKPLPF------------VGNILAYRHGFWEFD 61

  Fly    62 RH----EGKIVGIYMLNKRSILIRDAQLARQIMTSD-FASFHDR-----------GVYVDEDKDP 110
            ||    .|.|.|.|...:..:.|.|..:.:.::..: :::|.:|           .:.:.||::
  Rat    62 RHCHKKYGDIWGFYEGRQPILAITDPDIIKTVLVKECYSTFTNRRSFGPAGILKKAITLSEDEE- 125

  Fly   111 LSANLFNLRGASWRNLRQKLTPSFSSGKIKGMFGTIDDVGDKLVQHLEGALDQSDEVEIKDVMTT 175
                        |:.||..|:|:|:|||:|.||..|:...|.||::::...::.:.:.:||:...
  Rat   126 ------------WKRLRTLLSPTFTSGKLKEMFPIINQYADLLVKNVKHEAEKGNPITMKDIFGA 178

  Fly   176 YAVDIIGSVIFGLEIDSFRNPKNEF-REISSSTSRDESLLLKIH-----NMSMFICP---PIAKL 231
            |::|:|....||:.:||..||:|.| :::..        |||.:     .:|:.:.|   |:.:.
  Rat   179 YSMDVITGTSFGVNVDSLNNPQNPFVQKVKK--------LLKFNFLDPFFLSVILFPFLTPVFEA 235

  Fly   232 MNRLGYESRILTSLRDMMKRTIEFREEHNV-VRKDMLQLLIRLRNTGKIGEDDDQVWDMETAQEQ 295
            .:...:...::...|..::|..|.|.:..| .|.|.|||:|..:::|          |.|:.|
  Rat   236 FDITVFPKDVMKFFRTSVERMKENRMQEKVKQRLDFLQLMINSQSSG----------DKESHQ-- 288

  Fly   296 LKSMSIEKIAAQAFLFYVAGSESTAAASAFTLYELSMYPELLKEAQEEVDAVLMKHNLKPKDRFT 360
              .::..:|.||:..|..||.|:|::|.:|.||.|:.:|:|.|:.|:|:||.|..     |...|
  Rat   289 --GLTDVEIVAQSIFFIFAGYETTSSALSFALYLLATHPDLQKKLQDEIDAALPN-----KAPVT 346

  Fly   361 YEAVQDLKFLDICIMETIRKYPGLPFLNRECTEDYPVPGTNHIIAKGTPILISLFGMQRDPVYFP 425
            |:.:.::::||:.:.||:|.:|....|.|.|.:|..:.|.  .|.|||.:::..|.:.:||..:|
  Rat   347 YDVLVEMEYLDMVLNETLRLFPVGGRLERVCKKDVEINGV--FIPKGTVVMVPTFALHKDPKCWP 409

  Fly   426 NPNGYDPHRFDSNNM-NYDQAAYMPFGEGPRHCIALRMGKVNSKVAVAKILANFDLVQSPRKEVE 489
            .|..:.|.||...|. :.:...|:|||.|||:||.:|...:|.|:|:.::|.||........::.
  Rat   410 EPEEFCPERFRKKNQDSINPYIYLPFGNGPRNCIGMRFALMNMKIALVRVLQNFSFGLCKETQIP 474

  Fly   490 FRFDAAPVLVTKEPLKLRLTKR 511
            .:.........::|:.||...|
  Rat   475 LKLRKKGFFQPEKPIILRAVSR 496

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp6d2	NP_611698.1	p450	65..506	CDD:278495	125/463 (27%)
Cyp3a62	NP_001019403.1	p450	39..491	CDD:278495	133/505 (26%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0158
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D264519at33208
OrthoFinder	1	1.000	-	-		FOG0000037
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X40
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	7	6.820