Protein Alignment Cyp6d2 and cyp3a4.1

DIOPT Version :9

• Sequence 1: NP_611698.1
• Gene: Cyp6d2 / 37594
• FlyBaseID: FBgn0034756
• Length: 512
• Species: Drosophila melanogaster
• Sequence 2: XP_002943949.2
• Gene: cyp3a4.1 / 100494419
• XenbaseID: XB-GENE-984218
• Length: 504
• Species: Xenopus tropicalis
• Alignment Length: 535
• Identity: 149/535 - (27%)
• Similarity: 264/535 - (49%)
• Gaps: 72/535 - (13%)

  Fly     2 WTILLTILIAGLLYRYVKRHYTHWQRLGVDEEPAKIPFGVMDTVMKQERSLGMALADIYA-RHEG 65
            |.:|..:|:..|||....  |..::::|:   |...|...:.|.::..:  ||...||.. :..|
 Frog    12 WILLAVLLVLILLYGIWP--YGLFKKMGI---PGPTPLPFIGTFLEFRK--GMIQFDIECFKKYG 69

  Fly    66 KIVGIYMLNKRSILIRDAQLARQIMTSD-FASFHDR---GVYVDEDKDPLSANLFNLRGASWRNL 126
            ::.|:|...:..:.|.|..:.:.|:..: :.:|.:|   |:     ..||.:.:.......|:.:
 Frog    70 RMWGMYDGRQPVLAIMDPAIIKTILVKECYTNFTNRRNFGL-----NGPLESAITVAEDEQWKRI 129

  Fly   127 RQKLTPSFSSGKIKGMFGTIDDVGDKLVQHLEGALDQSDEVEIKDVMTTYAVDIIGSVIFGLEID 191
            |..|:|:|:|||:|.||..:.|..|.||::::.::|:.:....|||:..|::|:|.|..|.:.||
 Frog   130 RSVLSPTFTSGKLKEMFQIMKDYSDILVKNVQVSVDKDEPCATKDVIGAYSMDVITSTSFSVNID 194

  Fly   192 SFRNPKNEFREISSSTSRDESLLLKIHNM--SMFICP------------PIAKLMNRLGYESRIL 242
            |.:||.|.|             ::.|.|:  :.|:.|            ||.:::| :.:..:..
 Frog   195 SLQNPSNPF-------------VIHIKNLLKTGFLSPVIIFAVIFPFLRPIFEVLN-ISFFPKDF 245

  Fly   243 TSLRDMMKRTIEFRE-----EHNVVRKDMLQLLIRLRNTGKIGEDDDQVWDMETAQEQLKSMSIE 302
            |..  .|.....|||     :|: .|.|:|||::....|    |.:|       :..|.|:::..
 Frog   246 TQF--FMNAVTSFREKRKKGDHS-GRVDLLQLMVDSGTT----EGND-------SSNQHKALTDA 296

  Fly   303 KIAAQAFLFYVAGSESTAAASAFTLYELSMYPELLKEAQEEVDAVLMKHNLKPKDRFTYEAVQDL 367
            :|.||:.:|..||.|:|:.|.::..|.|:.:|::.::..||:|:.     |..|...||:.:..:
 Frog   297 EIMAQSLIFIFAGYETTSTALSYLFYNLATHPDVQQKLHEEIDSF-----LPDKASPTYDILMQM 356

  Fly   368 KFLDICIMETIRKYPGLPFLNRECTEDYPVPGTNHIIAKGTPILISLFGMQRDPVYFPNPNGYDP 432
            ::||:.|.||:|.:|....|.|...::..:.|.:  |.|||..:|..:.:||||.|:|.|..:.|
 Frog   357 EYLDMVIQETLRLFPPAGRLERVSKQNVEINGVS--IPKGTVAMIPAYVLQRDPEYWPEPEEFRP 419

  Fly   433 HRFD-SNNMNYDQAAYMPFGEGPRHCIALRMGKVNSKVAVAKILANFDLVQSPRKEVEFRFDAAP 496
            .||. .|........::|||:|||:||.||...::.|||:|.:|.||.:.......:...|....
 Frog   420 ERFSKENRATQTPFTFLPFGDGPRNCIGLRFALLSMKVAIATLLQNFSVRPCAETLIPMEFSTIG 484

  Fly   497 VLVTKEPLKLRLTKR 511
            ||..|:|:.|:...|
 Frog   485 VLQPKKPIVLKFLSR 499

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp6d2	NP_611698.1	p450	65..506	CDD:278495	132/464 (28%)
cyp3a4.1	XP_002943949.2	p450	39..496	CDD:365848	140/498 (28%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D264519at33208
OrthoFinder	1	1.000	-	-		FOG0000037
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X40
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	3.010