DRSC/TRiP Functional Genomics Resources

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back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment Cyp6d2 and LOC100487846

DIOPT Version :9

Sequence 1:NP_611698.1 Gene:Cyp6d2 / 37594 FlyBaseID:FBgn0034756 Length:512 Species:Drosophila melanogaster
Sequence 2:XP_017950484.2 Gene:LOC100487846 / 100487846 -ID:- Length:512 Species:Xenopus tropicalis


Alignment Length:533 Identity:139/533 - (26%)
Similarity:260/533 - (48%) Gaps:64/533 - (12%)


- Green bases have known domain annotations that are detailed below.


  Fly     2 WTILLTILIAGLLYRYVKRHYTHWQRLGVDEEPAKIPF---------GVMDTVMKQERSLGMALA 57
            ||:|  :|:..||..|....|..::|.|: ..|..|||         |:|:..||          
 Frog    12 WTLL--VLLLTLLAYYAIWPYRLFKRYGI-PGPTPIPFIGTFLGNRHGLMEFDMK---------- 63

  Fly    58 DIYARHEGKIVGIYMLNKRSILIRDAQLARQIMT----SDFASFHDRGVYVDEDKDPLSANLFNL 118
             .:.:: |.:.|.|...:..:.|.|..:.:.||.    ::|.:..|.|:     ..||.:::...
 Frog    64 -CFKKY-GNVWGFYDGPQPVLAILDPVIIKSIMVKECYTNFTNRRDFGL-----SGPLKSSVLMS 121

  Fly   119 RGASWRNLRQKLTPSFSSGKIKGMFGTIDDVGDKLVQHLEGALDQSDEVEIKDVMTTYAVDIIGS 183
            :...|:.:|..|:|:|:|||:|.||..:...|:.||:::...:|..:.:::|.:..:|::|.|.|
 Frog   122 KDEQWKRIRTVLSPTFTSGKLKQMFPLMKHYGELLVKNIHKKIDNKEPLDMKSIFGSYSMDTILS 186

  Fly   184 VIFGLEIDSFRNPKNEF----REISSSTSRDESLLLKIHNMSMFICPPIAKLMNRLGY---ESRI 241
            ..|.:.:||..||.:.|    |.:.:.:......|:.|      :||.:...::::.:   .|:.
 Frog   187 TSFSVNVDSMNNPNDPFVTNARNLFTFSFFKPLFLITI------LCPFLVPFLDKMNFCFLSSKF 245

  Fly   242 LTSLRDMMKRTIEFREE-HNVVRKDMLQLLIRLR-NTGKIGEDDDQVWDMETAQEQLKSMSIEKI 304
            |...:|.:....:.|:: .::.|.|.|||::..: |.|:...:::        :.:.|.:|..:|
 Frog   246 LKFFKDAVASIKKKRQKGAHMDRVDFLQLMVDAQSNEGESVPEEE--------KHRHKELSDTEI 302

  Fly   305 AAQAFLFYVAGSESTAAASAFTLYELSMYPELLKEAQEEVDAVLMKHNLKPKDRFTYEAVQDLKF 369
            .||:.:|.:||.|:|:....|..|.::.||::.::.:||::.:|  .|..|.   ||:|:..:::
 Frog   303 LAQSLIFIMAGYETTSTTLMFLTYNIARYPDVQRKLEEEINTLL--PNKAPP---TYDALMKMEY 362

  Fly   370 LDICIMETIRKYPGLPFLNRECTEDYPVPGTNHIIAKGTPILISLFGMQRDPVYFPNPNGYDPHR 434
            :|:.|.||:|..|....::|.|.:...:.|..  |..|..|::.||.:..:|..:|.|..:.|.|
 Frog   363 MDMVINETLRLLPPAIRIDRVCKKTMEINGVT--IPAGVVIVVPLFALHLNPEIWPEPEEFQPER 425

  Fly   435 FDSNNM-NYDQAAYMPFGEGPRHCIALRMGKVNSKVAVAKILANFDLVQSPRKEVEFRFDAAPVL 498
            |...|. |.|...::|||.|||:||.:|...||.|:|:..:|.||.|.......|..:......|
 Frog   426 FSKENQKNQDPYNFLPFGVGPRNCIGMRFALVNIKLALTILLQNFKLETCKDTPVPLKVCTRGNL 490

  Fly   499 VTKEPLKLRLTKR 511
            ...:|:.|.|..:
 Frog   491 KPTKPIILNLVPK 503

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Cyp6d2NP_611698.1 p450 65..506 CDD:278495 119/454 (26%)
LOC100487846XP_017950484.2 cytochrome_P450 67..498 CDD:425388 119/457 (26%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 1 1.010 - - D264519at33208
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
11.010

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