Protein Alignment Cyp6d2 and Cyp3a59

DIOPT Version :9

• Sequence 1: NP_611698.1
• Gene: Cyp6d2 / 37594
• FlyBaseID: FBgn0034756
• Length: 512
• Species: Drosophila melanogaster
• Sequence 2: NP_001098630.1
• Gene: Cyp3a59 / 100041449
• MGIID: 3769707
• Length: 503
• Species: Mus musculus
• Alignment Length: 534
• Identity: 147/534 - (27%)
• Similarity: 266/534 - (49%)
• Gaps: 73/534 - (13%)

  Fly     2 WTILLTILIAGLLYRYVKRHYTH--WQRLGVDEEPAKIPFGVMDTVMKQERSLGMALADIYARHE 64
            |.:|:|    .|::.|:...|:|  :::||:   |...|..:..|:......:.....|.|.::
Mouse    12 WVLLVT----SLVFFYIYGTYSHGLFKKLGI---PGPKPLPLFGTIFNYFDGMWKFDEDCYKKY- 68

  Fly    65 GKIVGIYMLNKRSILIRDAQLARQIMTSDFAS------------FHDRGVYVDEDKDPLSANLFN 117
            |||.|.|:..|..:.|.|.::.:.::..:..|            |..:.:.:.||::
Mouse    69 GKIWGFYVGPKPILAIMDPEIIKIVLVKECYSVFTNRPTLGPVGFLKKSITISEDEE-------- 125

  Fly   118 LRGASWRNLRQKLTPSFSSGKIKGMFGTIDDVGDKLVQHLEGALDQSDEVEIKDVMTTYAVDIIG 182
                 |:.||..|:|:|:|||:|.||..:...||.||::|....::.:.:.:||:...|::|:|.
Mouse   126 -----WKRLRTLLSPTFTSGKLKEMFPIMRQYGDILVRNLRREEEKGEPINMKDIFGAYSMDVIT 185

  Fly   183 SVIFGLEIDSFRNPKNEFREISSSTSRDESLLLKIHN---MSMFICP---PIAKLMNRLGYESRI 241
            ...||:.|||..||:|.|.:     ...:.|..||.:   :|..:.|   ||.:::|...:....
Mouse   186 GTSFGVNIDSLNNPQNPFVQ-----KTKKILKFKIFDPFLLSTILFPFLTPIYEMLNLSIFPRDS 245

  Fly   242 LTSLRDMMKRTIEFR---EEHNVVRKDMLQLLIRLRNTGKIGEDDDQVWDMETAQEQLKSMSIEK 303
            :...:..:||..:.|   ::.|  |.|.|||::..:|:              ..||..|::|..:
Mouse   246 MNFFKKFVKRMKKERLASKQKN--RVDFLQLMMNTQNS--------------KGQESQKALSDLE 294

  Fly   304 IAAQAFLFYVAGSESTAAASAFTLYELSMYPELLKEAQEEVDAVLMKHNLKPKDRFTYEAVQDLK 368
            :||||.:|...|.::|:.:.:..:|||:.:|::.|:.|:|:|     ..|..|...||:|:.|::
Mouse   295 MAAQAVIFIFGGYDATSTSISLIMYELATHPDVQKKLQDEID-----RTLPNKAPVTYDALMDME 354

  Fly   369 FLDICIMETIRKYPGLPFLNRECTEDYPVPGTNHIIAKGTPILISLFGMQRDPVYFPNPNGYDPH 433
            :||:.:.|::|.||....|.|...:|..:.|.  .|.|||.::|.::.:.|:|.|:|.|..:.|.
Mouse   355 YLDMVVNESLRLYPTAIRLERVSKKDVEINGV--FIPKGTVVMIPIYPLHRNPEYWPEPQEFCPG 417

  Fly   434 RFDSNNM-NYDQAAYMPFGEGPRHCIALRMGKVNSKVAVAKILANFDLVQSPRKEVEFRFDAAPV 497
            ||...|. |.|...|||||.|||:|:.:|...::.|:||..:|.||.:......::..:....||
Mouse   418 RFSKENEGNIDPYIYMPFGNGPRNCLDMRFALISMKLAVIGVLQNFTVQPCEETQIPLKISREPV 482

  Fly   498 LVTKEPLKLRLTKR 511
            ...::|:.|::..|
Mouse   483 FQPEKPIILKVVSR 496

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp6d2	NP_611698.1	p450	65..506	CDD:278495	131/462 (28%)
Cyp3a59	NP_001098630.1	p450	39..493	CDD:278495	137/495 (28%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0158
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D264519at33208
OrthoFinder	1	1.000	-	-		FOG0000037
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X40
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	6	5.820