Protein Alignment Cyp6d2 and Cyp3a41b

DIOPT Version :10

• Sequence 1: NP_611698.1
• Gene: Cyp6d2 / 37594
• FlyBaseID: FBgn0034756
• Length: 512
• Species: Drosophila melanogaster
• Sequence 2: NP_001098629.1
• Gene: Cyp3a41b / 100041375
• MGIID: 3714859
• Length: 504
• Species: Mus musculus
• Alignment Length: 528
• Identity: 148/528 - (28%)
• Similarity: 264/528 - (50%)
• Gaps: 60/528 - (11%)

  Fly     2 WTILLTILIAGLLYRYVKRHYTHWQRLGVDEEPAKIPFGVMDTVMKQERSLGMALADIYARHEGK 66
            |.:|..||:  |||||..|.:..:::.|: ..|..:||  :.||:...:.|.....:.|.:: ||
Mouse    12 WVLLAIILV--LLYRYGTRTHGLFKKQGI-PGPKPLPF--LGTVLNYYKGLWKFDMECYEKY-GK 70

  Fly    67 IVGIYMLNKRSILIRDAQLARQIMTSD-FASFHDR-----------GVYVDEDKDPLSANLFNLR 119
            ..|::.......:|.|.::.:.::..: |:.|.:|           .:.:.:|::
Mouse    71 TWGLFDGQMPLFVITDPEMIKNVLVKECFSVFTNRREFGPVGIMSKAISISKDEE---------- 125

  Fly   120 GASWRNLRQKLTPSFSSGKIKGMFGTIDDVGDKLVQHLEGALDQSDEVEIKDVMTTYAVDIIGSV 184
               |:..|..|:|:|:|||:|.||..|:..||.||::|....::...|.:|||:..|::|:|.|.
Mouse   126 ---WKRYRALLSPTFTSGKLKEMFPVIEQYGDILVKYLMQEAEKGKPVTMKDVLGAYSIDVITST 187

  Fly   185 IFGLEIDSFRNPKNEFREISSSTSRDESLLLKIHNMSMF-ICPPIAKLMNRLGYESRILTSLRDM 248
            .||:.:||..||::.|.|.:....|.:.....:.::.:| ...|:.:::|...:....:...:..
Mouse   188 SFGVNVDSLNNPEDPFVEKAKGILRVDFFDPLVFSVVLFPFLTPVYEMLNICMFPKDSIEFFKKF 252

  Fly   249 MKRTIEFR----EEHNVVRKDMLQLLIRLRNTGKIGEDDDQVWDMETAQEQLKSMSIEKIAAQAF 309
            :.|..|.|    ::|.|   |.|||::...|..|..:....:.|||             |.||:.
Mouse   253 VNRMKESRLDSKQKHRV---DFLQLMMNAHNNSKDKDSHKALSDME-------------ITAQSI 301

  Fly   310 LFYVAGSESTAAASAFTLYELSMYPELLKEAQEEVDAVLMKHNLKPKDRFTYEAVQDLKFLDICI 374
            :|..||.|:|::..:||||.|:.:|::.|:.|||:|..|  .|..|.   ||:.|.::::||:.:
Mouse   302 VFIFAGYETTSSTLSFTLYCLATHPDIQKKLQEEIDETL--PNKAPP---TYDTVMEMEYLDMVL 361

  Fly   375 METIRKYPGLPFLNRECTEDYPVPGTNHIIAKGTPILISLFGMQRDPVYFPNPNGYDPHRFDSNN 439
            .||:|.||....|.|.|.:|..:.|.  .|.||:.::|..:.:..||.::|.|..:.|.||...|
Mouse   362 NETLRLYPIGNRLERFCKKDVELNGV--YIPKGSTVMIPSYALHHDPQHWPEPEEFQPERFSKEN 424

  Fly   440 M-NYDQAAYMPFGEGPRHCIALRMGKVNSKVAVAKILANFDLVQSPRKEVEFRFDAAPVLVTKEP 503
            . :.|...|||||.|||:||.:|...:..|:|:.|::.||........::..:.....:|..::|
Mouse   425 KGSIDPYLYMPFGIGPRNCIGMRFAFMTMKLALTKVMQNFSFQPCQETQIPLKLSRQGLLQPEKP 489

  Fly   504 LKLRLTKR 511
            :.|::..|
Mouse   490 IVLKVVPR 497

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp6d2	NP_611698.1	CYP6-like	63..505	CDD:410679	128/459 (28%)
Cyp3a41b	NP_001098629.1	CYP3A	67..493	CDD:410743	128/462 (28%)