DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG2852 and CPR6

DIOPT Version :9

Sequence 1:	NP_611695.1	Gene:	CG2852 / 37591	FlyBaseID:	FBgn0034753	Length:	205	Species:	Drosophila melanogaster
Sequence 2:	NP_013317.1	Gene:	CPR6 / 850914	SGDID:	S000004206	Length:	371	Species:	Saccharomyces cerevisiae

Alignment Length:	189	Identity:	99/189 - (52%)
Similarity:	121/189 - (64%)	Gaps:	15/189 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly    30 KVFFDITIGGEPAGRIEIGLFGKTVPKTVENFKELA--------LKPQGE-GYKGSKFHRIIKDF 85
            |.||||:|||:|.|||...|:...||||.|||.:|.        .||... .||||.|||:||||
Yeast     5 KTFFDISIGGKPQGRIVFELYNDIVPKTAENFLKLCEGNAGMAKTKPDVPLSYKGSIFHRVIKDF 69

  Fly    86 MIQGGDFTKGDGTGGRSIYGERFEDENFKLKHYGAGWLSMANAGKDTNGSQFFITTKQTSWLDGR 150
            |.|.||||..:||||.|||.|:||||||.:||.....|||||||.:|||||.|||...|..|||:
Yeast    70 MCQFGDFTNFNGTGGESIYDEKFEDENFTVKHDKPFLLSMANAGPNTNGSQAFITCVPTPHLDGK 134

  Fly   151 HVVFGKILSGMNVVRQIENSATD-ARDRPVKDVVIANSGTLPVSEAFSV---AKADATD 205
            |||||:::.|..:||.|||...| ..::|::||.|.:.|.||  :.:.|   |:|..||
Yeast   135 HVVFGEVIQGKRIVRLIENQQCDQENNKPLRDVKIDDCGVLP--DDYQVPENAEATPTD 191

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG2852	NP_611695.1	cyclophilin	30..188	CDD:294131	91/167 (54%)
CPR6	NP_013317.1	cyclophilin_ABH_like	4..173	CDD:238907	91/167 (54%)
		TPR repeat	219..264	CDD:276809
		TPR repeat	269..303	CDD:276809
		TPR repeat	308..334	CDD:276809
		TPR_1	311..341	CDD:395414
		TPR repeat	342..368	CDD:276809
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0652
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000032
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.810