Protein Alignment CG2852 and PPIAL4A

DIOPT Version :10

• Sequence 1: NP_611695.1
• Gene: CG2852 / 37591
• FlyBaseID: FBgn0034753
• Length: 205
• Species: Drosophila melanogaster
• Sequence 2: NP_001137355.1
• Gene: PPIAL4A / 653505
• HGNCID: 24369
• Length: 164
• Species: Homo sapiens
• Alignment Length: 377
• Identity: 76/377 - (20%)
• Similarity: 126/377 - (33%)
• Gaps: 83/377 - (22%)

  Fly   177 VFYLSILIITVGRLVSMFTAAYYVV------FCIAAVVGSLTAHSIFQAPLIIAMEISKSERR-- 233
            :.||...:.|.|..:..|..:.::|      ..:.||.|.:.|.|:.....||...:.|:.|.
Human    27 LLYLGHSLSTWGDRMWHFAVSVFLVELYGNSLLLTAVYGLVVAGSVLVLGAIIGDWVDKNARLKV 91

  Fly   234 -------GHISMMQCIGWTTGLCILPMVFWATKDWF-----WAL-----LIVTMPIV--LFMFIP 279
                   .::|::.|     |: ||.|||....:..     |.|     ||:|:..:  |.....
Human    92 AQTSLVVQNVSVILC-----GI-ILMMVFLHKNELLTMYHGWVLTVCYILIITIANIANLASTAT 150

  Fly   280 SYTIESPRWLATRGNYREAMVQFRKIATINGIRELAFDERVLEKRLANHRTDKVYGLAS------ 338
            :.||:....:...|..|..:....  |||..|.:|.       ..||.....::....|
Human   151 AITIQRDWIVVVAGENRSRLADMN--ATIRRIDQLT-------NILAPMAVGQIMTFGSPVIGCG 206

  Fly   339 LFNGWRMAKNTMLVILCWTVCSVTYFTLVLLSSRMDGNPFLNFMYQGLIEVPAAFAGQRAADRFG 403
            ..:||.:....:...|.|.|...|....|..:.:::.:...........| |....|...   .|
Human   207 FISGWNLVSMCVEYFLLWKVYQKTPALAVKAALKVEESELKQLTSPKDTE-PKPLEGTHL---MG 267

  Fly   404 RRATNAMALCCATAVCLVLVLIVRDP--ANEMAATVLTTFVKFCISITFFGVNLQSIEIYPTCLR 466
            .:.:|...|.|.           ::|  |::||....|           |.....|....|..|
Human   268 EKDSNIRELECE-----------QEPTCASQMAEPFRT-----------FRDGWVSYYNQPVFL- 309

  Fly   467 QTGMAVGTIAATIFG---IVGPYVVHLGTEYDVRYPFLVMGLSSAVGILAAL 515
             .||.:..:..|:.|   |...|....|....:.  .::||.|:..||:..:
Human   310 -AGMGLAFLYMTVLGFDCITTGYAYTQGLSGSIL--SILMGASAITGIMGTV 358

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG2852	NP_611695.1	cyclophilin	30..188	CDD:469651	3/10 (30%)
PPIAL4A	NP_001137355.1	cyclophilin	4..162	CDD:469651	31/140 (22%)