DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG2852 and ppil4

DIOPT Version :9

Sequence 1:	NP_611695.1	Gene:	CG2852 / 37591	FlyBaseID:	FBgn0034753	Length:	205	Species:	Drosophila melanogaster
Sequence 2:	NP_001121802.1	Gene:	ppil4 / 554886	ZFINID:	ZDB-GENE-030131-6251	Length:	454	Species:	Danio rerio

Alignment Length:	163	Identity:	60/163 - (36%)
Similarity:	87/163 - (53%)	Gaps:	18/163 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly    31 VFFDITIGGEPAGRIEIGLFGKTVPKTVENFKELALKPQGEGYKGSKFHRIIKDFMIQGGDFTKG 95
            |..:.|:|.     |.|.|:.:..||...||.:|.   :.:.|.....|.:.:||:||.||.| |
Zfish     3 VLLETTLGD-----IVIDLYTEERPKASLNFLKLC---KIKYYNYCLIHNVQRDFIIQTGDPT-G 58

  Fly    96 DGTGGRSI----YGER---FEDENF-KLKHYGAGWLSMANAGKDTNGSQFFITT-KQTSWLDGRH 151
            .|.||.|:    ||::   ||.|.. ::||...|.:||.|.|.|.:||||.||| :...:|||.|
Zfish    59 TGRGGESVFCKLYGDQARFFESEKMPRIKHRKKGTVSMVNNGSDQHGSQFLITTGENVDYLDGVH 123

  Fly   152 VVFGKILSGMNVVRQIENSATDARDRPVKDVVI 184
            .|||::..||:|:.:|..:..|....|.:|:.|
Zfish   124 TVFGEVTEGMDVLAKINETFVDNDFIPFQDIRI 156

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG2852	NP_611695.1	cyclophilin	30..188	CDD:294131	60/163 (37%)
ppil4	NP_001121802.1	cyclophilin_RRM	4..169	CDD:238902	59/162 (36%)
		RRM	172..>320	CDD:223796
		RRM_PPIL4	237..319	CDD:240681
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0652
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.900