DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG2852 and PPIC

DIOPT Version :9

Sequence 1:	NP_611695.1	Gene:	CG2852 / 37591	FlyBaseID:	FBgn0034753	Length:	205	Species:	Drosophila melanogaster
Sequence 2:	NP_000934.1	Gene:	PPIC / 5480	HGNCID:	9256	Length:	212	Species:	Homo sapiens

Alignment Length:	180	Identity:	122/180 - (67%)
Similarity:	136/180 - (75%)	Gaps:	0/180 - (0%)

- Green bases have known domain annotations that are detailed below.

  Fly    23 KGPKVTEKVFFDITIGGEPAGRIEIGLFGKTVPKTVENFKELALKPQGEGYKGSKFHRIIKDFMI 87
            :||.||.|||||:.||.:..|||.||||||.||||||||..||...:|.|||||||||:||||||
Human    32 RGPSVTAKVFFDVRIGDKDVGRIVIGLFGKVVPKTVENFVALATGEKGYGYKGSKFHRVIKDFMI 96

  Fly    88 QGGDFTKGDGTGGRSIYGERFEDENFKLKHYGAGWLSMANAGKDTNGSQFFITTKQTSWLDGRHV 152
            ||||.|.||||||.|||||.|.||||||||||.||:||||||.||||||||||..:.:||||:||
Human    97 QGGDITTGDGTGGVSIYGETFPDENFKLKHYGIGWVSMANAGPDTNGSQFFITLTKPTWLDGKHV 161

  Fly   153 VFGKILSGMNVVRQIENSATDARDRPVKDVVIANSGTLPVSEAFSVAKAD 202
            ||||::.||.||..||..|||..|||:.:..|.|||.:.|...|.|..||
Human   162 VFGKVIDGMTVVHSIELQATDGHDRPLTNCSIINSGKIDVKTPFVVEIAD 211

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG2852	NP_611695.1	cyclophilin	30..188	CDD:294131	111/157 (71%)
PPIC	NP_000934.1	cyclophilin	39..197	CDD:294131	111/157 (71%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0652
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53630
OrthoDB	1	1.010	-	-		D1403619at2759
OrthoFinder	1	1.000	-	-		FOG0000032
OrthoInspector	1	1.000	-	-		otm40844
orthoMCL	1	0.900	-	-		OOG6_100844
Panther	1	1.100	-	-	O	PTHR11071
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X987
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	10	9.790