Protein Alignment CG2852 and PPIB

DIOPT Version :10

• Sequence 1: NP_611695.1
• Gene: CG2852 / 37591
• FlyBaseID: FBgn0034753
• Length: 205
• Species: Drosophila melanogaster
• Sequence 2: NP_000933.1
• Gene: PPIB / 5479
• HGNCID: 9255
• Length: 216
• Species: Homo sapiens
• Alignment Length: 207
• Identity: 135/207 - (65%)
• Similarity: 167/207 - (80%)
• Gaps: 7/207 - (3%)

  Fly     1 MKLFLSVFVVA------LVAGVVVADD-SKGPKVTEKVFFDITIGGEPAGRIEIGLFGKTVPKTV 58
            ||:.|:..::|      |:.|...||: .||||||.||:||:.||.|..||:..|||||||||||
Human     9 MKVLLAAALIAGSVFFLLLPGPSAADEKKKGPKVTVKVYFDLRIGDEDVGRVIFGLFGKTVPKTV 73

  Fly    59 ENFKELALKPQGEGYKGSKFHRIIKDFMIQGGDFTKGDGTGGRSIYGERFEDENFKLKHYGAGWL 123
            :||..||...:|.|||.|||||:||||||||||||:||||||:|||||||.||||||||||.||:
Human    74 DNFVALATGEKGFGYKNSKFHRVIKDFMIQGGDFTRGDGTGGKSIYGERFPDENFKLKHYGPGWV 138

  Fly   124 SMANAGKDTNGSQFFITTKQTSWLDGRHVVFGKILSGMNVVRQIENSATDARDRPVKDVVIANSG 188
            ||||||||||||||||||.:|:||||:||||||:|.||.|||::|::.||:||:|:|||:||:.|
Human   139 SMANAGKDTNGSQFFITTVKTAWLDGKHVVFGKVLEGMEVVRKVESTKTDSRDKPLKDVIIADCG 203

  Fly   189 TLPVSEAFSVAK 200
            .:.|.:.|::||
Human   204 KIEVEKPFAIAK 215

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG2852	NP_611695.1	cyclophilin	30..188	CDD:469651	116/157 (74%)
PPIB	NP_000933.1	cyclophilin_ABH_like	45..203	CDD:238907	116/157 (74%)
		Prevents secretion from ER	213..216		2/3 (67%)