DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG2852 and ppib

DIOPT Version :9

Sequence 1:	NP_611695.1	Gene:	CG2852 / 37591	FlyBaseID:	FBgn0034753	Length:	205	Species:	Drosophila melanogaster
Sequence 2:	NP_998184.1	Gene:	ppib / 406292	ZFINID:	ZDB-GENE-040426-1955	Length:	216	Species:	Danio rerio

Alignment Length:	210	Identity:	145/210 - (69%)
Similarity:	166/210 - (79%)	Gaps:	13/210 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MKLFLSVFVVALVAGVVV---------ADD-SKGPKVTEKVFFDITIGGEPAGRIEIGLFGKTVP 55
            ||..::   |.|:.|.||         ||: .||||||.||:|||.||.|.||||.|||||||||
Zfish     9 MKFLVA---VTLIVGSVVFLLFPSETEADEKKKGPKVTAKVYFDIKIGDEDAGRIVIGLFGKTVP 70

  Fly    56 KTVENFKELALKPQGEGYKGSKFHRIIKDFMIQGGDFTKGDGTGGRSIYGERFEDENFKLKHYGA 120
            ||.|||.:||...:|.|||||||||:||||||||||||:||||||:||||:||.||||||||||.
Zfish    71 KTTENFLQLATGEKGFGYKGSKFHRVIKDFMIQGGDFTRGDGTGGKSIYGDRFPDENFKLKHYGP 135

  Fly   121 GWLSMANAGKDTNGSQFFITTKQTSWLDGRHVVFGKILSGMNVVRQIENSATDARDRPVKDVVIA 185
            |||||||||||||||||||||.||.||||:||||||||.||:|||:||.:.||.||:|:|||.|.
Zfish   136 GWLSMANAGKDTNGSQFFITTVQTPWLDGKHVVFGKILEGMDVVRKIEATKTDGRDKPLKDVSIH 200

  Fly   186 NSGTLPVSEAFSVAK 200
            :||.:.|.:.|:|||
Zfish   201 DSGKIDVEKPFAVAK 215

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG2852	NP_611695.1	cyclophilin	30..188	CDD:294131	123/157 (78%)
ppib	NP_998184.1	cyclophilin_ABH_like	45..203	CDD:238907	123/157 (78%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	254	1.000	Domainoid score	I2021
eggNOG	1	0.900	-	-		E1_COG0652
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H726
Inparanoid	1	1.050	284	1.000	Inparanoid score	I2849
OMA	1	1.010	-	-		QHG53630
OrthoDB	1	1.010	-	-		D1403619at2759
OrthoFinder	1	1.000	-	-		FOG0000032
OrthoInspector	1	1.000	-	-		oto39163
orthoMCL	1	0.900	-	-		OOG6_100844
Panther	1	1.100	-	-	LDO	PTHR11071
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R961
SonicParanoid	1	1.000	-	-		X987
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	16	15.870