DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG2852 and cwc27

DIOPT Version :9

Sequence 1:	NP_611695.1	Gene:	CG2852 / 37591	FlyBaseID:	FBgn0034753	Length:	205	Species:	Drosophila melanogaster
Sequence 2:	NP_957397.1	Gene:	cwc27 / 394078	ZFINID:	ZDB-GENE-040426-1118	Length:	470	Species:	Danio rerio

Alignment Length:	153	Identity:	63/153 - (41%)
Similarity:	92/153 - (60%)	Gaps:	10/153 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly    42 AGRIEIGLFGKTVPKTVENFKELALKPQGEG-YKGSKFHRIIKDFMIQGGDFTKGDGTGGRSIYG 105
            ||.|:|.|:.|..||...||.:|.:    || |.|:.|||::.:|::||||.| |.||||.||||
Zfish    21 AGDIDIELWSKETPKACRNFVQLCM----EGYYDGTIFHRMVPEFIVQGGDPT-GTGTGGESIYG 80

  Fly   106 ERFEDE-NFKLKHYGAGWLSMANAGKDTNGSQFFITTKQTSWLDGRHVVFGKILSG--MNVVRQI 167
            ..|:|| :.:|:....|.::|||||...||||||.|..:...|:.:|.:|||:...  .|::| :
Zfish    81 RPFKDEFHSRLRFNRRGLVAMANAGPHDNGSQFFFTLGRADELNNKHTIFGKVTGDTVYNMLR-L 144

  Fly   168 ENSATDARDRPVKDVVIANSGTL 190
            .:.|.|..:||:....|.::..|
Zfish   145 ADVACDGDERPLNPHKIRSTEVL 167

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG2852	NP_611695.1	cyclophilin	30..188	CDD:294131	62/149 (42%)
cwc27	NP_957397.1	cyclophilin_CeCYP16-like	8..178	CDD:238906	63/153 (41%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	172..377
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	428..470
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0652
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.810