DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG2852 and CG8336

DIOPT Version :9

Sequence 1:	NP_611695.1	Gene:	CG2852 / 37591	FlyBaseID:	FBgn0034753	Length:	205	Species:	Drosophila melanogaster
Sequence 2:	NP_001261636.1	Gene:	CG8336 / 39121	FlyBaseID:	FBgn0036020	Length:	383	Species:	Drosophila melanogaster

Alignment Length:	182	Identity:	79/182 - (43%)
Similarity:	110/182 - (60%)	Gaps:	9/182 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly    31 VFFDITIGGEPAGRIEIGLFGKTVPKTVENFKELALKPQGEG-------YKGSKFHRIIKDFMIQ 88
            |:.||:||.|.|||:.|.|....||||.|||:.|.....|.|       |||:|||:|.:.|::|
  Fly    17 VYLDISIGKEDAGRMIIELRKDVVPKTAENFRALCTGECGIGTLGKPLHYKGTKFHKIKRVFVVQ 81

  Fly    89 GGDFTKGDGTGGRSIYGERFEDENFKLKHYGAGWLSMANAGK-DTNGSQFFITTKQTSWLDGRHV 152
            .||..|.||:.|.||||..|:||||:|.|...|.:||||.|| ::|.|||||:......|:|.:|
  Fly    82 SGDVVKNDGSSGESIYGPVFDDENFELSHNEEGVVSMANYGKPNSNNSQFFISAAGCENLNGTNV 146

  Fly   153 VFGKILSGMNVVRQIENSATDARDRPVKDVVIANSGTLPVSEAFSVAKADAT 204
            |.|::|.|:.:|.::|.:.||..| |...:||.:.|.:..:|.:.:...|.|
  Fly   147 VVGRVLRGLGIVAEMEQNCTDEGD-PTAPIVIRDCGEIAHNEDWGIECNDET 197

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG2852	NP_611695.1	cyclophilin	30..188	CDD:294131	75/164 (46%)
CG8336	NP_001261636.1	cyclophilin	15..181	CDD:294131	75/164 (46%)
		TPR repeat	285..315	CDD:276809
		TPR_19	300..369	CDD:291240
		TPR_1	320..353	CDD:278916
		TPR repeat	320..346	CDD:276809
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45447198
Domainoid	1	1.000	81	1.000	Domainoid score	I449
eggNOG	1	0.900	-	-		E1_COG0652
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1403619at2759
OrthoFinder	1	1.000	-	-		FOG0000032
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11071
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	7	6.850