DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG2852 and cyp33

DIOPT Version :9

Sequence 1:	NP_611695.1	Gene:	CG2852 / 37591	FlyBaseID:	FBgn0034753	Length:	205	Species:	Drosophila melanogaster
Sequence 2:	NP_523773.1	Gene:	cyp33 / 36984	FlyBaseID:	FBgn0028382	Length:	300	Species:	Drosophila melanogaster

Alignment Length:	180	Identity:	98/180 - (54%)
Similarity:	120/180 - (66%)	Gaps:	8/180 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly    18 VADDSKGPKVTEK-------VFFDITIGGEPAGRIEIGLFGKTVPKTVENFKELALKPQGEGYKG 75
            |...|.||.|.||       |||||.|||..||||.:.|....||||.|||::|....||.||||
  Fly   121 VETPSTGPAVIEKAEKRNPQVFFDIRIGGNDAGRIVMLLRADVVPKTAENFRQLCTHEQGYGYKG 185

  Fly    76 SKFHRIIKDFMIQGGDFTKGDGTGGRSIYGERFEDENFKLKHYGAGWLSMANAGKDTNGSQFFIT 140
            ..|||:|.:||.||||||..:||||:||||::|.||||.|||...|.|||||:|.:||||||||.
  Fly   186 CSFHRVIPEFMCQGGDFTNNNGTGGKSIYGKKFNDENFNLKHNSFGTLSMANSGANTNGSQFFIC 250

  Fly   141 TKQTSWLDGRHVVFGKILSGMNVVRQIENSATDARDRPVKDVVIANSGTL 190
            |.:|.|||.:|||||.::||..|||::|...:.: ..|.:.:||.:.|.|
  Fly   251 TTKTDWLDNKHVVFGHVISGAEVVRKMERCGSKS-GTPSQKIVIYSCGEL 299

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG2852	NP_611695.1	cyclophilin	30..188	CDD:294131	90/164 (55%)
cyp33	NP_523773.1	RRM_PPIE	8..80	CDD:240793
cyp33	NP_523773.1	cyclophilin_ABH_like	139..297	CDD:238907	89/158 (56%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45447223
Domainoid	1	1.000	81	1.000	Domainoid score	I449
eggNOG	1	0.900	-	-		E1_COG0652
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11071
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	5	4.840