DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG2852 and wis2

DIOPT Version :9

Sequence 1:	NP_611695.1	Gene:	CG2852 / 37591	FlyBaseID:	FBgn0034753	Length:	205	Species:	Drosophila melanogaster
Sequence 2:	NP_594787.1	Gene:	wis2 / 2542541	PomBaseID:	SPAC1B3.03c	Length:	356	Species:	Schizosaccharomyces pombe

Alignment Length:	177	Identity:	97/177 - (54%)
Similarity:	117/177 - (66%)	Gaps:	6/177 - (3%)

- Green bases have known domain annotations that are detailed below.

  Fly    32 FFDITIGGEPAGRIEIGLFGKTVPKTVENFKELALKPQGEG----YKGSKFHRIIKDFMIQGGDF 92
            :|.|:|.|:....|...||...|||||:||..|....:.:|    ||||:|||:||:||:|||||
pombe     6 YFKISIDGKIQPTIYFELFDNVVPKTVKNFASLCNGFEKDGRCLTYKGSRFHRVIKNFMLQGGDF 70

  Fly    93 TKGDGTGGRSIYGERFEDENFKLKHYGAGWLSMANAGKDTNGSQFFITTKQTSWLDGRHVVFGKI 157
            |:|:||||.|||||:||||||:|||.....|||||||.:||||||||||..|..|||:||||||:
pombe    71 TRGNGTGGESIYGEKFEDENFELKHDKPFLLSMANAGPNTNGSQFFITTVPTPHLDGKHVVFGKV 135

  Fly   158 LSGMNVVRQIENSATDARDRPVKDVVIANSGTLPVSEAFSVAKADAT 204
            :.|.:.||.|||..| ..|.||..|||...||. ..:.....|.|.|
pombe   136 IQGKSTVRTIENLET-KNDDPVVPVVIEECGTC-TKDQIEAPKPDVT 180

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG2852	NP_611695.1	cyclophilin	30..188	CDD:294131	92/159 (58%)
wis2	NP_594787.1	cyclophilin	6..165	CDD:294131	92/159 (58%)
		TPR_11	204..287	CDD:290150
		TPR repeat	204..253	CDD:276809
		TPR repeat	258..288	CDD:276809
		TPR_11	261..323	CDD:290150
		TPR repeat	293..323	CDD:276809
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0652
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000032
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.810