DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG2852 and cyn-4

DIOPT Version :9

Sequence 1:	NP_611695.1	Gene:	CG2852 / 37591	FlyBaseID:	FBgn0034753	Length:	205	Species:	Drosophila melanogaster
Sequence 2:	NP_496337.1	Gene:	cyn-4 / 174674	WormBaseID:	WBGene00000880	Length:	523	Species:	Caenorhabditis elegans

Alignment Length:	197	Identity:	73/197 - (37%)
Similarity:	103/197 - (52%)	Gaps:	13/197 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly    14 AGVVVADDSKGPKVTEKVFFDITIGGEPAGRIEIGLFGKTVPKTVENFKELALKPQGEG-YKGSK 77
            |.|:..|..:..:|.:..|..:...   .|.:.:.||...|||..|||    :.....| |..:|
Worm   263 AAVLDNDTVRYSRVKKNAFVRLVTN---FGPLNLELFAPKVPKACENF----ITHCSNGYYNNTK 320

  Fly    78 FHRIIKDFMIQGGDFTKGDGTGGRSIYGERFEDENFK-LKHYGAGWLSMANAGKDTNGSQFFITT 141
            |||:||:||:||||.| |.|.||.||:.:.|.||... ..|...|.|||||.|.:|||||||||.
Worm   321 FHRLIKNFMLQGGDPT-GTGHGGESIWDKPFSDEFISGFSHDARGVLSMANKGSNTNGSQFFITF 384

  Fly   142 KQTSWLDGRHVVFGKILSGMNVVRQIENSAT-DARDRPVKDVVIANSGTL--PVSEAFSVAKADA 203
            :...:||.:|.:||:::.|.:.:..||...| :..|.|:..|||..:...  |..||....:|:.
Worm   385 RPCKYLDRKHTIFGRLVGGQDTLTTIEKLETEEGTDVPMVSVVIMRAEVFVDPFEEAEKEVQAER 449

  Fly   204 TD 205
            .:
Worm   450 AE 451

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG2852	NP_611695.1	cyclophilin	30..188	CDD:294131	65/160 (41%)
cyn-4	NP_496337.1	Ubox	45..96	CDD:128780
cyn-4	NP_496337.1	cyclophilin_RING	281..440	CDD:238904	66/166 (40%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0652
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.810