DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG2852 and cyn-5

DIOPT Version :9

Sequence 1:	NP_611695.1	Gene:	CG2852 / 37591	FlyBaseID:	FBgn0034753	Length:	205	Species:	Drosophila melanogaster
Sequence 2:	NP_001379232.1	Gene:	cyn-5 / 173374	WormBaseID:	WBGene00000881	Length:	204	Species:	Caenorhabditis elegans

Alignment Length:	200	Identity:	142/200 - (71%)
Similarity:	160/200 - (80%)	Gaps:	0/200 - (0%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MKLFLSVFVVALVAGVVVADDSKGPKVTEKVFFDITIGGEPAGRIEIGLFGKTVPKTVENFKELA 65
            ||..|.|..|..|..:...||:||||||:||:||:.|||:|.|||.|||||||||||..||.|||
Worm     1 MKSLLVVAAVLAVGALAQGDDAKGPKVTDKVYFDMEIGGKPIGRIVIGLFGKTVPKTATNFIELA 65

  Fly    66 LKPQGEGYKGSKFHRIIKDFMIQGGDFTKGDGTGGRSIYGERFEDENFKLKHYGAGWLSMANAGK 130
            .||:||||.||||||:|.||||||||||:||||||||||||:|.||||||||||||||||||||.
Worm    66 KKPKGEGYPGSKFHRVIADFMIQGGDFTRGDGTGGRSIYGEKFADENFKLKHYGAGWLSMANAGA 130

  Fly   131 DTNGSQFFITTKQTSWLDGRHVVFGKILSGMNVVRQIENSATDARDRPVKDVVIANSGTLPVSEA 195
            |||||||||||.:|.|||||||||||||.||:|||:||.:.....|||.:||:||.||.:.|...
Worm   131 DTNGSQFFITTVKTPWLDGRHVVFGKILEGMDVVRKIEQTEKLPGDRPKQDVIIAASGHIAVDTP 195

  Fly   196 FSVAK 200
            |||.:
Worm   196 FSVER 200

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG2852	NP_611695.1	cyclophilin	30..188	CDD:294131	122/157 (78%)
cyn-5	NP_001379232.1	cyclophilin	29..188	CDD:412213	122/158 (77%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160167452
Domainoid	1	1.000	253	1.000	Domainoid score	I1124
eggNOG	1	0.900	-	-		E1_COG0652
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H726
Inparanoid	1	1.050	290	1.000	Inparanoid score	I1694
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53630
OrthoDB	1	1.010	-	-		D1403619at2759
OrthoFinder	1	1.000	-	-		FOG0000032
OrthoInspector	1	1.000	-	-		otm14535
orthoMCL	1	0.900	-	-		OOG6_100844
Panther	1	1.100	-	-	LDO	PTHR11071
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R961
SonicParanoid	1	1.000	-	-		X987
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	16	15.840