Protein Alignment Ugt317A1 and Ugt1a6a

DIOPT Version :10

• Sequence 1: NP_611694.2
• Gene: Ugt317A1 / 37590
• FlyBaseID: FBgn0040091
• Length: 529
• Species: Drosophila melanogaster
• Sequence 2: NP_659545.2
• Gene: Ugt1a6a / 94284
• MGIID: 2137698
• Length: 531
• Species: Mus musculus
• Alignment Length: 568
• Identity: 136/568 - (23%)
• Similarity: 233/568 - (41%)
• Gaps: 102/568 - (17%)

  Fly     8 WILLAILGLALGQISQAAKILVLFPHVNEGHFAVMRTLVTELANREHTIEVYTGHG---LGES-- 67
            ::.|.:....||.     |:||: |. :..|:..|:.:|..|:.|.|.|.|.....   ||||
Mouse    15 FLFLVLWASVLGD-----KLLVV-PQ-DGSHWLSMKEIVEHLSERGHDIMVLVPEVNLLLGESKY 72

  Fly    68 ----LDNVTETVTAEFPFWSELQKQAAPKGN---LADLGLL-PIEKLRQSLASVGARALDHFLAQ 124
                :.:||.::       .|||.:....||   |....|: |:.:.|.::..|     |.|.:.
Mouse    73 YRRKIFSVTYSL-------EELQTRFRTFGNNHFLPGASLMGPLREYRNNMIVV-----DMFFSN 125

  Fly   125 EPIQKLLK----MSYL-EFDFDVILVDYFYTEALLALGALHQRPVV--GIISTDFGN----YM-- 176
              .|.|||    :|:| |..||.:..|                |.:  |:|..::.|    |:
Mouse   126 --CQSLLKDSATLSFLRENKFDALFTD----------------PAMPCGVILAEYLNLPSVYLFR 172

  Fly   177 --DAVQEALVPAACSPID-----FERDQPEMSFSVRLGN---------IRTCIARRKQFIKDHYG 225
              ....|.::..:.||:.     :.:....|:|..||.|         :..|:          |.
Mouse   173 GFPCSLEHMLGQSPSPVSYVPRFYTKFSDHMTFPQRLANFIVNILENYLYYCL----------YS 227

  Fly   226 GQEQLVTKYFQLQSSIPELQASQLSVLLLNSHVPLITPKVSIQQIIPAGGLHIRGPKELPWNVKR 290
            ..|.:.:...:...|:|.|.  |.|:.||........|:..:..:|..||::.:...:|....:.
Mouse   228 KYEIIASDLLKRDVSLPSLH--QNSLWLLRYDFVFEYPRPVMPNMIFLGGINCKKKGKLTQEFEA 290

  Fly   291 FLE-EARPGAIYVQLGNEQACGQLPKEKLDTLFAFFSARKQSIIWTCHDVKTLEGLPKNVMIQHA 354
            ::. ....|.:...||:  ...::|::|...:........|:::|.....:. ..|.||.::...
Mouse   291 YVNASGEHGIVVFSLGS--MVSEIPEKKAMEIAEALGRIPQTVLWRYTGTRP-SNLAKNTILVKW 352

  Fly   355 VPQIDILAHPRVKAFLTNGDLLNLQEGIMRNVPILGLPLFQHEARNMELAVRLGVGLQLEEGNVT 419
            :||.|:|.||:.:||:|:.....:.|||...||::.:|||..:..|.:.....|.|:.|....:|
Mouse   353 LPQNDLLGHPKTRAFITHSGSHGIYEGICNGVPMVMMPLFGDQMDNAKRMETRGAGVTLNVLEMT 417

  Fly   420 TESLNWAVDRLLLESHFQLTIRDVSLEFRDRPLGALASALFWVNYVARHKGGSALRTRGIGISSC 484
            .:.|..|:..::....::..|..:|...:|||:..|..|:|||.||.||||...||.....::..
Mouse   418 ADDLENALKTVINNKSYKENIMRLSSLHKDRPIEPLDLAVFWVEYVMRHKGAPHLRPAAHDLTWY 482

  Fly   485 QLHLFDLFVFYAGIATLVVSLLVAL-------SFGGFYIWNKKNNSKS 525
            |.|..|:..|...|...||.::...       .|||.....|.:.||:
Mouse   483 QYHSLDVIGFLLAIVLTVVFIVFKCCAYGCRKCFGGKGRVKKSHKSKT 530

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ugt317A1	NP_611694.2	GT1_Gtf-like	25..431	CDD:340817	102/448 (23%)
Ugt1a6a	NP_659545.2	UDPGT	27..522	CDD:278624	130/546 (24%)