Protein Alignment Ugt317A1 and ugt2a5

DIOPT Version :10

• Sequence 1: NP_611694.2
• Gene: Ugt317A1 / 37590
• FlyBaseID: FBgn0040091
• Length: 529
• Species: Drosophila melanogaster
• Sequence 2: NP_001070111.2
• Gene: ugt2a5 / 767705
• ZFINID: ZDB-GENE-060929-796
• Length: 532
• Species: Danio rerio
• Alignment Length: 528
• Identity: 121/528 - (22%)
• Similarity: 221/528 - (41%)
• Gaps: 57/528 - (10%)

  Fly    10 LLAILGLALGQISQAAKILVLFPHVNEGHFAVMRTLVTELANREHTIEVYTGHGLGESLDNVTET 74
            ||..|.|....:..:.::||:....:  |:..||.::..|.::.|::.|.    :|.|...|..|
Zfish     6 LLVCLLLCGVDVGWSGRVLVMPGEYS--HWHNMRPVIEALVDKNHSVTVL----VGSSSPTVPHT 64

  Fly    75 VTAEFP---FWSELQKQAAPKGNLADLGLLPIEKLRQSLASVGARALDHFLAQEPIQKLLKMS-- 134
            ....|.   |...::|:.|... :.|:       :........|:....|:..:.:.|.::..
Zfish    65 QKERFEYHVFKVNMEKEEADAA-MRDM-------IHLFTNDTAAKYEGEFVMWKVMSKFVEFGDV 121

  Fly   135 YLEFDFDVILV--------DYFYTEALLALGALHQR----PVVGIISTDFGNYMDAV------QE 181
            |....|||.|:        |..:::.::....|..:    |.|..:...|....:.:      ..
Zfish   122 YFRGLFDVGLLKTLRDSNYDVLFSDPMMPFSDLMAQKLNIPQVISMRATFAYAAERLCGQMPAPP 186

  Fly   182 ALVPAACSPIDFERDQPEMSFSVRLGNIRTCIARR------KQFIKDHYGGQEQLVTKYFQLQSS 240
            :.|||. :..|...|:  |||..|:.|:...|...      ..|..|.|  ..:::.|...:..:
Zfish   187 SYVPAV-ALTDHLTDR--MSFMERVENMLLYIVHSIAFPLVATFTFDGY--YSEILGKPTTMCET 246

  Fly   241 IPELQASQLSVLLLNSHVPLITPKVSIQQIIPAGGLHIRGPKELPWNVKRFLEEARP-GAIYVQL 304
            :     .::.:.|:.::.....|:.........||||.:..|.|...::.|::.:.. |.:...|
Zfish   247 M-----GKVDICLIRTYWDFEYPRPFPPNFKFVGGLHCKPAKPLSKELEEFVQSSGDHGVVVFSL 306

  Fly   305 GNEQACGQLPKEKLDTLFAFFSARKQSIIWTCHDVKTLEGLPKNVMIQHAVPQIDILAHPRVKAF 369
            |:  ....|..|:.:|:.|......|.::|. :..||.|.|..|..|...:||.|:|.||:.|||
Zfish   307 GS--MIKNLTSERANTIAAALGQIPQKVVWR-YSGKTPETLAPNTKIYDWIPQNDLLGHPKTKAF 368

  Fly   370 LTNGDLLNLQEGIMRNVPILGLPLFQHEARNMELAVRLGVGLQLEEGNVTTESLNWAVDRLLLES 434
            :|:|....|.|.|...||::|||||..:..|:......|..:.|:...:.::.|..|:..::...
Zfish   369 ITHGGTNGLYEAIYHGVPMVGLPLFGDQPDNLLHIKTKGAAVVLDIHTMGSKDLVDALKAVVNNP 433

  Fly   435 HFQLTIRDVSLEFRDRPLGALASALFWVNYVARHKGGSALRTRGIGISSCQLHLFDLFVFYAGIA 499
            .::.:|..:|....|:|:..|..|::|:.:|.|:||...||.:...:|..|.|..|:..|...|.
Zfish   434 SYKESIMRLSRIHHDQPMKPLDQAVYWIEFVMRNKGAKHLRVQAHELSWYQYHCLDVAAFLLSIT 498

  Fly   500 TLVVSLLV 507
            .|:..|.|
Zfish   499 ALITFLWV 506

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ugt317A1	NP_611694.2	GT1_Gtf-like	25..431	CDD:340817	95/435 (22%)
ugt2a5	NP_001070111.2	UDPGT	21..519	CDD:278624	117/513 (23%)