DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Ugt317A1 and Ugt2a1

DIOPT Version :9

Sequence 1:	NP_001286734.1	Gene:	Ugt317A1 / 37590	FlyBaseID:	FBgn0040091	Length:	529	Species:	Drosophila melanogaster
Sequence 2:	XP_038948318.1	Gene:	Ugt2a1 / 63867	RGDID:	69432	Length:	528	Species:	Rattus norvegicus

Alignment Length:	550	Identity:	119/550 - (21%)
Similarity:	221/550 - (40%)	Gaps:	100/550 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly    11 LAILGLALGQISQAAKILVLFPHVNEG-HFAVMRTLVTELANREHTIEV---------------- 58
            |.|..|||.:|..:..: |::|  ::| |:..::.|:.||..|.|::.|
  Rat     8 LLIFPLALTEIVLSGNV-VIWP--SDGSHWLNIKILLEELVQRNHSVTVLAASETLFINSSPDAF 69

  Fly    59 ---------YTGHGLGESLDNV-------TETVTAEFPFWSELQKQAAPKGNLADLGLLPIEKLR 107
                     ||...:.|.::::       ..|....:.|:.||                  .||.
  Rat    70 ISFEEIPVSYTRSKIDEMIEHMIALWLDHRPTPLTMWAFYKEL------------------GKLF 116

  Fly   108 QSLASVGARALDHFLAQEPIQKLLKMSYLEFDFDVILVD----------------YFYTEALLAL 156
            .:...:..:..|..|....:...|:..    .|||::.|                :.||
  Rat   117 AAFYKINKQICDGVLKNATLMARLQKG----GFDVLISDPVTMCGELVALKLGIPFVYT------ 171

  Fly   157 GALHQRPVVGIISTDFGNYMDAVQEALVPAACSPIDFERDQPEMSFSVRLGNIRTCIARRKQFI- 220
              |...|.. .:....|.....|  :.||||.|.:   .||  |:|..|:.|  |.....:.:|
  Rat   172 --LRFSPAF-TVERHCGKIPTPV--SYVPAALSEL---TDQ--MTFGERVKN--TISYSLQDYIF 224

  Fly   221 KDHYGGQEQLVTKYFQLQSSIPELQASQLSVLLLNSHVPLITPKVSIQQIIPAGGLHIRGPKELP 285
            |.::|......::.....:::.|.. .:..:.|:.::.....|:..:......||||.:..|.||
  Rat   225 KSYWGEWNSYYSRVLGRPTTLCETM-GKAEIWLMRTYWDFEFPRPYLPNFEFVGGLHCKPAKPLP 288

  Fly   286 WNVKRFLE-EARPGAIYVQLGNEQACGQLPKEKLDTLFAFFSARKQSIIWTCHDVKTLEGLPKNV 349
            ..::.|:: ....|.:...||:  ....|.:||.:.:.:..:...|.::|. :..|....|..|.
  Rat   289 KEMEEFVQTSGEHGVVVFSLGS--MVKNLTEEKANLIASALAQIPQKVLWR-YKGKIPATLGSNT 350

  Fly   350 MIQHAVPQIDILAHPRVKAFLTNGDLLNLQEGIMRNVPILGLPLFQHEARNMELAVRLGVGLQLE 414
            .:...:||.|:|.||:.:||:|:|....:.|.|...:|::|:|:|..:..|:......|..:::.
  Rat   351 RLFDWIPQNDLLGHPKTRAFITHGGTNGIYEAIYHGIPMVGVPMFADQPDNIAHMKAKGAAVEVN 415

  Fly   415 EGNVTTESLNWAVDRLLLESHFQLTIRDVSLEFRDRPLGALASALFWVNYVARHKGGSALRTRGI 479
            ...:|:..|..||..::.|..::.....:|....|:|:..|..|:||:.:|.||||...||....
  Rat   416 MNTMTSADLLSAVRAVINEPFYKENAMRLSRIHHDQPVKPLDRAVFWIEFVMRHKGAKHLRVAAH 480

  Fly   480 GISSCQLHLFDLFVFYAGIATLVVSLLVAL 509
            .:|..|.|..|:..|.  :|.:..::|:.:
  Rat   481 DLSWFQYHSLDVIGFL--LACMASAILLVI 508

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ugt317A1	NP_001286734.1	Glycosyltransferase_GTB_type	22..477	CDD:299143	106/505 (21%)
Ugt317A1	NP_001286734.1	UDPGT	25..514	CDD:278624	113/535 (21%)
Ugt2a1	XP_038948318.1	UDPGT	22..524	CDD:278624	113/535 (21%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000004
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.910