Protein Alignment Ugt317A1 and Ugt1a8

DIOPT Version :9

• Sequence 1: NP_001286734.1
• Gene: Ugt317A1 / 37590
• FlyBaseID: FBgn0040091
• Length: 529
• Species: Drosophila melanogaster
• Sequence 2: NP_001365304.1
• Gene: Ugt1a8 / 613123
• MGIID: 3576090
• Length: 530
• Species: Mus musculus
• Alignment Length: 542
• Identity: 127/542 - (23%)
• Similarity: 235/542 - (43%)
• Gaps: 48/542 - (8%)

  Fly     7 RWILLAILGLALGQISQAAKILVLFPHVNEGHFAVMRTLVTELANREHTIEV----YTGHGLGES 67
            |..||...|||     ||.::||:  .::..|:..|:.:|.:|::|.|.:.|    .:.| ||:|
Mouse    13 RVCLLLAFGLA-----QAGRLLVV--PMDGSHWFSMKMIVEKLSHRGHEVVVVIPEVSWH-LGKS 69

  Fly    68 LDNVT----------ETVTAEFPFWSELQKQAAPKGNLADLGLLPIEKLRQSLASVGARALDHFL 122
             .|.|          |.::..|.|::..|.:.      .::|:..:  |:.|..........|..
Mouse    70 -QNFTVKTYSVSYTLEDLSHHFNFFAHKQWEN------REVGMFSL--LKHSGKGFFQVLFSHCR 125

  Fly   123 AQEPIQKLLKMSYL-EFDFDVILVDYFYTEALLALGALHQRPVVGIISTDFGNYMDAVQEALVPA 186
            :....:||::  || :..||.:.:|.| ....|.:......|.|......|.:|:|...:...|.
Mouse   126 SLFNDKKLVE--YLKQRSFDAVFLDPF-DVCGLTIAKYFSLPSVVFSGGIFCHYLDEGAQCPSPP 187

  Fly   187 ACSPIDFERDQPEMSFSVRLGNIRTCIARRKQFIKDHYGGQEQLVTKYFQLQSSIPELQASQLSV 251
            :..|....:....|:|..|:.|..:.: :.:.|....:....::.::..|...::.:| .|.:|:
Mouse   188 SYVPRILSKFADTMTFKERVWNYFSYM-KERAFCPYFFKTAIEIASEVLQTPVTMTDL-FSSVSI 250

  Fly   252 LLLNSHVPLITPKVSIQQIIPAGGLHIRGPKELPWNVKRFLE-EARPGAIYVQLGNEQACGQLPK 315
            .:..:...|..|:..:..::..||::....|.|....:.::. ....|.:...||:  ...::|:
Mouse   251 WMFRTDFVLEFPRPVMPNMVYIGGINCHPGKPLSKEFEAYVNASGEHGIVVFSLGS--MVSEIPE 313

  Fly   316 EKLDTLFAFFSARKQSIIWTCHDVKTLEGLPKNVMIQHAVPQIDILAHPRVKAFLTNGDLLNLQE 380
            :|...:........|:::|.....:. ..|.||.::...:||.|:|.||:.:||:|:.....:.|
Mouse   314 KKAMEIAEALGRIPQTVLWRYTGTRP-SNLAKNTILVKWLPQNDLLGHPKTRAFITHSGSHGIYE 377

  Fly   381 GIMRNVPILGLPLFQHEARNMELAVRLGVGLQLEEGNVTTESLNWAVDRLLLESHFQLTIRDVSL 445
            ||...||::.:|||..:..|.:.....|.|:.|....:|.:.|..|:..::....::..|..:|.
Mouse   378 GICNGVPMVMMPLFGDQMDNAKRMETRGAGVTLNVLEMTADDLENALKTVINNKSYKENIMRLSS 442

  Fly   446 EFRDRPLGALASALFWVNYVARHKGGSALRTRGIGISSCQLHLFDLFVFYAGIATLVVSLLVAL- 509
            ..:|||:..|..|:|||.||.||||...||.....::..|.|..|:..|...|...||.::...
Mouse   443 LHKDRPIEPLDLAVFWVEYVMRHKGAPHLRPAAHDLTWYQYHSLDVIGFLLAIVLTVVFIVFKCC 507

  Fly   510 ------SFGGFYIWNKKNNSKS 525
                  .|||.....|.:.||:
Mouse   508 AYGCRKCFGGKGRVKKSHKSKT 529

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ugt317A1	NP_001286734.1	Glycosyltransferase_GTB_type	22..477	CDD:299143	108/470 (23%)
		UDPGT	25..514	CDD:278624	115/511 (23%)
Ugt1a8	NP_001365304.1	UDPGT	26..521	CDD:278624	116/514 (23%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E33208_3BDT1
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000004
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.810