Protein Alignment Ugt317A1 and UGT1A9

DIOPT Version :9

• Sequence 1: NP_001286734.1
• Gene: Ugt317A1 / 37590
• FlyBaseID: FBgn0040091
• Length: 529
• Species: Drosophila melanogaster
• Sequence 2: NP_066307.1
• Gene: UGT1A9 / 54600
• HGNCID: 12541
• Length: 530
• Species: Homo sapiens
• Alignment Length: 542
• Identity: 127/542 - (23%)
• Similarity: 221/542 - (40%)
• Gaps: 85/542 - (15%)

  Fly     5 WNRWILLAILGLALGQISQAAKILVLFPHVNEGHFAVMRTLVTELANREHTIEVY---TGHGLGE 66
            |...:.|.:..|.....::|.|:||:  .::..|:..||::|.:|..|.|.:.|.   ....||.
Human     6 WTSPLPLCVCLLLTCGFAEAGKLLVV--PMDGSHWFTMRSVVEKLILRGHEVVVVMPEVSWQLGR 68

  Fly    67 SLDNVTETVTA---------EFPFWSELQKQAAPK-------GNLADLGLLPIEKLRQSLASVGA 115
            ||:...:|.:.         ||..::..|.:|..:       |:..|:
Human    69 SLNCTVKTYSTSYTLEDLDREFKAFAHAQWKAQVRSIYSLLMGSYNDI----------------- 116

  Fly   116 RALDHFLAQEPIQKLLK----MSYL-EFDFDVILVDYFYTEALLALGALHQRPVV---GIISTDF 172
              .|.|.:.  .:.|.|    :.|| |..||.:.:|.|....|:.........||   ||:.
Human   117 --FDLFFSN--CRSLFKDKKLVEYLKESSFDAVFLDPFDNCGLIVAKYFSLPSVVFARGILC--- 174

  Fly   173 GNYMDAVQEALVPAACSPIDFERDQPEMSFSVRLGNIRTCIARRKQFIKDHYGGQEQLVTKYFQ- 236
             :|::...:...|.:..|.........|:|..|:.|       ....:::|.     |..::|:
Human   175 -HYLEEGAQCPAPLSYVPRILLGFSDAMTFKERVRN-------HIMHLEEHL-----LCHRFFKN 226

  Fly   237 --------LQSSIPELQA-SQLSVLLLNSHVPLITPKVSIQQIIPAGGLHIRGPKELPWNVKRFL 292
                    ||:.:.|... |..|:.||.:...|..||..:..:|..||::....|.||...:.::
Human   227 ALEIASEILQTPVTEYDLYSHTSIWLLRTDFVLDYPKPVMPNMIFIGGINCHQGKPLPMEFEAYI 291

  Fly   293 E-EARPGAIYVQLGNEQACGQLPKEKLDTLFAFFSARKQSIIWTCHDVKTLEGLPKNVMIQHAVP 356
            . ....|.:...||:  ...::|::|...:........|:::|.....:. ..|..|.::...:|
Human   292 NASGEHGIVVFSLGS--MVSEIPEKKAMAIADALGKIPQTVLWRYTGTRP-SNLANNTILVKWLP 353

  Fly   357 QIDILAHPRVKAFLTNGDLLNLQEGIMRNVPILGLPLFQHEARNMELAVRLGVGLQLEEGNVTTE 421
            |.|:|.||..:||:|:.....:.|.|...||::.:|||..:..|.:.....|.|:.|....:|:|
Human   354 QNDLLGHPMTRAFITHAGSHGVYESICNGVPMVMMPLFGDQMDNAKRMETKGAGVTLNVLEMTSE 418

  Fly   422 SLNWAVDRLLLESHFQLTIRDVSLEFRDRPLGALASALFWVNYVARHKGGSALRTRGIGISSCQL 486
            .|..|:..::.:..::..|..:|...:|||:..|..|:|||.:|.||||...||.....::..|.
Human   419 DLENALKAVINDKSYKENIMRLSSLHKDRPVEPLDLAVFWVEFVMRHKGAPHLRPAAHDLTWYQY 483

  Fly   487 HLFDLFVFYAGIATLVVSLLVA 508
            |..|:..|     .|.|.|.||
Human   484 HSLDVIGF-----LLAVVLTVA 500

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ugt317A1	NP_001286734.1	Glycosyltransferase_GTB_type	22..477	CDD:299143	115/492 (23%)
		UDPGT	25..514	CDD:278624	123/522 (24%)
UGT1A9	NP_066307.1	UDPGT	26..521	CDD:278624	123/522 (24%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E33208_3BDT1
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000004
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.810