DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ugt317A1 and Ugt37C1

DIOPT Version :9

Sequence 1:	NP_001286734.1	Gene:	Ugt317A1 / 37590	FlyBaseID:	FBgn0040091	Length:	529	Species:	Drosophila melanogaster
Sequence 2:	NP_525007.1	Gene:	Ugt37C1 / 53583	FlyBaseID:	FBgn0026754	Length:	485	Species:	Drosophila melanogaster

Alignment Length:	498	Identity:	122/498 - (24%)
Similarity:	215/498 - (43%)	Gaps:	87/498 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly    60 TGHGLGESLDNVTETVTAEFPFWSELQKQAAPKGNLADLGLL--PIEK-----LRQSLASVGA-- 115
            |...|.|:..|||..        |.:|    ||....|:.|:  |:.|     |...:||:..
  Fly     3 TAKALAEAGHNVTVV--------SMMQ----PKVMHKDIHLIVVPVTKEQERTLENQMASMAGSK 55

  Fly   116 -----------RALDHFLAQEPIQKLLK----MSYLEFDFDVILVDYFYTEALLALGALHQRPVV 165
                       ..||..:..:  ..|||    ....|..||::::..|:.:..|.:....:.||:
  Fly    56 NNIITTMYLLLNGLDVMVTSQ--ADLLKDPRFQRVFETKFDLMILGSFFNDFQLGVAGKLKVPVI 118

  Fly   166 GIISTDFGNYMDAVQEALVPAACSPIDFERDQPEMSFSVRLGNIRTCIARRKQFIKDHYGGQEQL 230
                .|:          ::|:.....:|..:..|:|:   :.|..|.......|.|......:.:
  Fly   119 ----VDW----------MIPSNTMIDEFVANPSEVSY---VPNESTFATTPMSFFKRAENLVKHV 166

  Fly   231 VTKYFQLQ---------------SSIPEL--QASQLSVLLLNSHVPLITPKVSIQQIIPA----G 274
            :.||..::               ..:|.|  ....:|::.:.||:....|   |:.::||    |
  Fly   167 ILKYLTIRFNYKFNRIYNEIFTDKDMPTLSEMKKNISMVFVGSHLISDGP---IRPLVPAIIEVG 228

  Fly   275 GLHIR-GPKELPWNVKRFLEEARPGAIYVQLGNEQACGQLPKEKLDTLFAFFSARKQSIIWTCHD 338
            |:.:: .|..||.::::|:|.:..|||::..|:......:..|.:..:|...|..||::||...|
  Fly   229 GIQVKEQPDPLPQDIEQFMENSSQGAIFLSFGSNIKSYMVKPEIVGIMFKVLSGLKQNVIWKWED 293

  Fly   339 VKTLEGLPKNVMIQHAVPQIDILAHPRVKAFLTNGDLLNLQEGIMRNVPILGLPLFQHEARNMEL 403
            ::...|...|:..:..:||.||||||..|.|:|:....::.|.....||::.||:|.....|..|
  Fly   294 LENTPGNASNIFYKDWLPQDDILAHPNTKLFVTHAGKGSITESQYHGVPMVALPIFGDHPLNAAL 358

  Fly   404 AVRLGVGLQLEEGNVTTESLNWAVDRLLLESHFQLTIRDVSLEFRDRPLGALASALFWVNYVARH 468
            .|..|.|:.|:...:|.::...|::.:|....:...:|..|..:|||||....|.||||:||.||
  Fly   359 MVNSGYGVSLDLQTITEDTFREAINEVLENDKYTQAVRKFSALYRDRPLTPRQSVLFWVDYVLRH 423

  Fly   469 KGGSALRTRGIGISSCQLHLFDLFVFYAGIATLVVSLLVALSF 511
            .|...|::..:.:...:||..|::       .||:::|:.|.|
  Fly   424 HGAPNLQSPAVHMGFVELHNLDIY-------ALVLAILIFLVF 459

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ugt317A1	NP_001286734.1	Glycosyltransferase_GTB_type	22..477	CDD:299143	114/462 (25%)
Ugt317A1	NP_001286734.1	UDPGT	25..514	CDD:278624	122/498 (24%)
Ugt37C1	NP_525007.1	UDPGT	1..477	CDD:278624	122/498 (24%)
Ugt37C1	NP_525007.1	egt	6..433	CDD:223071	113/460 (25%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	76	1.000	Domainoid score	I3136
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D53444at6656
OrthoFinder	1	1.000	-	-		FOG0000004
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR48043
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	5	5.020