DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Ugt317A1 and Ugt37D1

DIOPT Version :9

Sequence 1:	NP_001286734.1	Gene:	Ugt317A1 / 37590	FlyBaseID:	FBgn0040091	Length:	529	Species:	Drosophila melanogaster
Sequence 2:	NP_001285989.1	Gene:	Ugt37D1 / 53511	FlyBaseID:	FBgn0040260	Length:	543	Species:	Drosophila melanogaster

Alignment Length:	569	Identity:	151/569 - (26%)
Similarity:	262/569 - (46%)	Gaps:	70/569 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MESQWNRWI-------LLAILGL-ALGQISQAAKILVLFPHVNEGHFAVMRTLVTELANREHTIE 57
            |....:.||       |:|:|.| .:.|.::.|.||.:|...:..||.|..:::..||.:.|.:.
  Fly     1 MTQNRSTWIGCSLGGLLVALLALQTMPQGTEGANILGVFTSHSPSHFIVHMSIMKTLAEKGHNVT 65

  Fly    58 VYTG------HGLGESLDNVTETVTAEFPFWSELQKQAAPKGNLADLGLLP-----IEKLRQSLA 111
            |.:.      |   :|::::...::||       .::....|....:...|     ::.:..|||
  Fly    66 VVSSVPPKVTH---KSINHIVVPMSAE-------DEKVLNDGMAGMVKEKPSIWNTMKSIFSSLA 120

  Fly   112 SVGARALDHFLAQEP-IQKLLKMSYLE--FDFDVILVDYFYTEALLALGALHQRPVVGIISTDFG 173
            .:..:.:|  :.::| .|:|    ||.  ..|||:.|.:|:....:||||....||  |||.. |
  Fly   121 LLIDKQVD--VLEDPRFQEL----YLNKGNKFDVVFVGFFFNTYQVALGARFNCPV--IISWS-G 176

  Fly   174 NYMDAVQEAL-------VPAACSPIDFERDQPEMSFSVRLGNIRTCIA--RRKQFIKDHYGGQEQ 229
            ..|..|.|.|       ||.  ..|.....|| |:|..|:.|..:.:.  ....|:...|   .:
  Fly   177 PPMMMVNEVLGNPELSSVPQ--MHISAPPGQP-MNFQQRMQNFASTLGFNALNIFLNHKY---NK 235

  Fly   230 LVTKYFQLQSSIPEL-QASQ-LSVLLLNSHVPLITP-KVSIQQIIPAGGLHIRG-PKELPWNVKR 290
            ...:.:....|:|.. ||.: :|:...|.|.....| :.::..:|..||:.::. |..||.:::.
  Fly   236 FYDRLWSKDKSMPTFAQAKRNVSLAFCNGHGISEGPIRPNVPGVIEIGGIQVKSKPDPLPEDIQE 300

  Fly   291 FLEEARPGAIYVQLGNEQACGQLPKEKLDTLFAFFSARKQSIIWTCHDVKTLEGLPKNVMIQHAV 355
            |||:.:.|||...||:......:..|.:.|:|...|:.||.:||...|.|...|...|::.:..:
  Fly   301 FLEKGKHGAILFSLGSNLKGEHIQPEVVKTIFKGLSSLKQQVIWKWEDPKNTPGKSANILYKKWL 365

  Fly   356 PQIDILAHPRVKAFLTNGDLLNLQEGIMRNVPILGLPLFQHEARNMELAVRLGVGLQLEEGNVTT 420
            ||.||||||::|.|:|:.....:.|.....||:|.||:|..:..|.:..|..|.||||....:..
  Fly   366 PQDDILAHPKLKLFITHAGKGGVAEAQYHGVPMLALPVFADQPGNADKLVASGYGLQLPLATLDV 430

  Fly   421 ESLNWAVDRLLLESHFQLTIRDVSLEFRDRPLGALASALFWVNYVARHKGGSALRTRGIGISSCQ 485
            :....|:..::....:..|::..|..:|||||....|.::|..||.||.|.:.:::..:.::...
  Fly   431 DEFKAAIKEVIENPKYAKTLKSFSQLYRDRPLSPQESVVYWTEYVIRHHGAAHMQSPLVHMNFIA 495

  Fly   486 LHLFDLFVFYAGIATLVVSLLVALS-FGGFYIWNK---KNN--SKSTKV 528
            .:..|:::    ||.||:.::..:: ....::|.|   |:|  ||..||
  Fly   496 SNNLDIYI----IAALVLYIVFIINKIVWKFVWRKLFGKSNKVSKGKKV 540

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ugt317A1	NP_001286734.1	Glycosyltransferase_GTB_type	22..477	CDD:299143	130/481 (27%)
Ugt317A1	NP_001286734.1	UDPGT	25..514	CDD:278624	135/516 (26%)
Ugt37D1	NP_001285989.1	egt	25..512	CDD:223071	136/515 (26%)
Ugt37D1	NP_001285989.1	UDPGT	45..530	CDD:278624	133/513 (26%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	76	1.000	Domainoid score	I3136
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D53444at6656
OrthoFinder	1	1.000	-	-		FOG0000004
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR48043
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	5	5.020