DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Ugt317A1 and Ugt35C1

DIOPT Version :9

Sequence 1:	NP_001286734.1	Gene:	Ugt317A1 / 37590	FlyBaseID:	FBgn0040091	Length:	529	Species:	Drosophila melanogaster
Sequence 2:	NP_001097744.1	Gene:	Ugt35C1 / 53507	FlyBaseID:	FBgn0040256	Length:	517	Species:	Drosophila melanogaster

Alignment Length:	523	Identity:	153/523 - (29%)
Similarity:	233/523 - (44%)	Gaps:	44/523 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly    10 LLAILGLALGQ---ISQAAKILVLFPHVNEGHFAVMRTLVTELANREHTIEVYTGHGLGESLDNV 71
            ::||:..||..   .|::||||...|......:..:.:.:..||.:.|.:.|.      .:..|
  Fly     6 VIAIVFCALSAKPLESESAKILATLPFPGRSQYIFVESYLKALAAKGHQVTVI------NAFKN- 63

  Fly    72 TETVTAEFPFWSELQKQAAPKGNLAD--LGLLPIEKLRQSLASVGARALDHFL--------AQEP 126
            .||....|       .:|......||  :.||.:..|.|.|     .|:|:.|        ..|.
  Fly    64 KETPNMRF-------IEALKAHEFADEMMSLLNVPLLWQQL-----NAMDYILNKFIDVTMEDEG 116

  Fly   127 IQKLLKMSYLEFDFDVILVDYFYTEALLALGALHQRPVVGIISTDFGNYMDAVQEALVPAACSPI 191
            :|:||....   .||::|.:..:.|.:.|........:||..|......:|.....:.|.:.:|:
  Fly   117 VQRLLNSGE---TFDLVLAEMLHMEPMYAFAQHFNATLVGFSSFGTDRTIDEAAGNISPISYNPL 178

  Fly   192 DFERDQPEMSFSVRLGNIRTCIAR--RKQFIKDHYGGQEQLVTKYFQLQSSIPELQASQLSVLLL 254
            ........|:|..||.|....|..  .:.|:  |......:..|||.......|......|::||
  Fly   179 VTSPRTDRMTFLERLENHYEVIVEDIHRHFV--HLPHMRNVYKKYFPNAKKTLEEVMDSFSLILL 241

  Fly   255 NSHVPLITPKVSIQQIIPAGGLHI-RGPKELPWNVKRFLEEARPGAIYVQLGNEQACGQLPKEKL 318
            ..|..|..|:..:..:|..||:|| ..||.||.::|:|:|.:..|.||..:|:......||:|..
  Fly   242 GQHFSLSYPRPYLPNMIEVGGMHISHKPKPLPEDIKQFIEGSPHGVIYFSMGSNVKSKDLPQETR 306

  Fly   319 DTLFAFFSARKQSIIWTCHDVKTLEGLPKNVMIQHAVPQIDILAHPRVKAFLTNGDLLNLQEGIM 383
            |||...|:..||.::|...| ..:.|.|.||:|:...||.||||||.||.|:::|.||:..|.:.
  Fly   307 DTLLKTFAKLKQRVLWKFED-DDMPGKPANVLIKKWYPQPDILAHPNVKLFISHGGLLSSTESVY 370

  Fly   384 RNVPILGLPLFQHEARNMELAVRLGVGLQLEEGNVTTESLNWAVDRLLLESHFQLTIRDVSLEFR 448
            ...||||||.|..:..|::.|.|:|.||.|:..|:..|.|..|:..||.:..:......:|..:|
  Fly   371 FGKPILGLPCFYDQHMNVQRAQRVGFGLGLDLNNLKQEDLEKAIQTLLTDPSYAKASLAISERYR 435

  Fly   449 DRPLGALASALFWVNYVARHKGGSALRTRGIGISSCQLHLFDLFVFYAGIATLVVSLLVALS--- 510
            |:|..|:..|::|..||.||.|...||.....::..||:..|.......:..|:..|:|.||
  Fly   436 DQPQSAVDRAVWWTEYVIRHNGAPHLRATSRDLNFIQLNSLDTLAVILAVPLLLALLIVTLSCKL 500

  Fly   511 FGG 513
            .||
  Fly   501 LGG 503

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ugt317A1	NP_001286734.1	Glycosyltransferase_GTB_type	22..477	CDD:299143	139/467 (30%)
Ugt317A1	NP_001286734.1	UDPGT	25..514	CDD:278624	148/505 (29%)
Ugt35C1	NP_001097744.1	egt	1..470	CDD:223071	143/488 (29%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	76	1.000	Domainoid score	I3136
eggNOG	1	0.900	-	-		E33208_3BDT1
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	89	1.000	Inparanoid score	I2281
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D53444at6656
OrthoFinder	1	1.000	-	-		FOG0000004
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR48043
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	7	6.970